Publications

Dey Hazra, Rony-Orijit; Hanhoff, Marek; Kühnapfel, Andreas; Rutledge, Joan C.; Warnhoff, Mara; Ellwein, Alexander et al.: Superior clinical results for early arthroscopic treatment of grade IIIb and V acromioclavicular joint instability compared to delayed operative treatment. Journal of shoulder and elbow surgery. DOI: 10.1016/j.jse.2022.11.023. (source)

Kanoni, Stavroula; Graham, Sarah E.; Wang, Yuxuan; Surakka, Ida; Ramdas, Shweta; Zhu, Xiang et al.: Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Genome Biol. 23 (1), S. 268. DOI: 10.1186/s13059-022-02837-1. (source)

Schwarze, Mandy; Luo, Ji; Brakel, Alexandra; Krizsan, Andor; Lakowa, Nicole; Grünewald, Thomas et al.: Evaluation of S- and M-Proteins Expressed in Escherichia coli and HEK Cells for Serological Detection of Antibodies in Response to SARS-CoV-2 Infections and mRNA-Based Vaccinations. Pathogens 11 (12). DOI: 10.3390/pathogens11121515. (source)

Kempf, Elena; Landgraf, Kathrin; Stein, Robert; Hanschkow, Martha; Hilbert, Anja; Abou Jamra, Rami et al.: Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. Nature metabolism. DOI: 10.1038/s42255-022-00703-9. (source)

Heydarian, Motaharehsadat; Oak, Prajakta; Zhang, Xin; Kamgari, Nona; Kindt, Alida; Koschlig, Markus et al.: Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant. Thorax 77 (12), S. 1176–1186. DOI: 10.1136/thoraxjnl-2021-218083. (source)

Gräfe, Daniel; Simion, Stefan-Horia; Rosolowski, Maciej; Merkenschlager, Andreas; Frahm, Jens; Voit, Dirk; Hirsch, Franz Wolfgang: Brain deposition of gadobutrol in children-a cross-sectional and longitudinal MRI T1 mapping study. European radiology. DOI: 10.1007/s00330-022-09297-y. (source)

Weitzel, Elena Caroline; Löbner, Margrit; Glaesmer, Heide; Hinz, Andreas; Zeynalova, Samira; Henger, Sylvia et al.: The Association of Resilience with Mental Health in a Large Population-Based Sample (LIFE-Adult-Study). International journal of environmental research and public health 19 (23). DOI: 10.3390/ijerph192315944. (source)

Stein, Anna; Metzeler, Klaus; Kubasch, Anne Sophie; Rommel, Karl-Philipp; Desch, Steffen; Buettner, Petra et al.: Clonal hematopoiesis and cardiovascular disease: deciphering interconnections. Basic research in cardiology 117 (1), S. 55. DOI: 10.1007/s00395-022-00969-w. (source)

Yengo, Loïc; Vedantam, Sailaja; Marouli, Eirini; Sidorenko, Julia; Bartell, Eric; Sakaue, Saori et al.: A saturated map of common genetic variants associated with human height. Nature. DOI: 10.1038/s41586-022-05275-y. (source)

Bracher, Johannes; Wolffram, Daniel; Deuschel, Jannik; Görgen, Konstantin; Ketterer, Jakob L.; Ullrich, Alexander et al.: National and subnational short-term forecasting of COVID-19 in Germany and Poland during early 2021. Communications medicine 2 (1), S. 136. DOI: 10.1038/s43856-022-00191-8. (source)

Böhme, Matthias; Desch, Steffen; Rosolowski, Maciej; Scholz, Markus; Krohn, Knut; Büttner, Petra et al.: Impact of Clonal Hematopoiesis in Patients With Cardiogenic Shock Complicating Acute Myocardial Infarction. J. Am. Coll. Cardiol. 80 (16), S. 1545–1556. DOI: 10.1016/j.jacc.2022.08.740. (source)

Wettin, Nils; Drogies, Tim; Kühnapfel, Andreas; Isermann, Berend; Thome, Ulrich Herbert: Automated Complete Blood Cell Count Using Sysmex XN-9000® in the Diagnosis of Newborn Infection. Journal of clinical medicine 11 (19). DOI: 10.3390/jcm11195507. (source)

Stürzebecher, Paulina Elena; Kralisch, Susan; Schubert, Marie Ruth; Filipova, Vanina; Hoffmann, Annett; Oliveira, Fabiana et al.: Leptin treatment has vasculo-protective effects in lipodystrophic mice. Proceedings of the National Academy of Sciences of the United States of America 119 (40), e2110374119. DOI: 10.1073/pnas.2110374119. (source)

Weitzel, Elena Caroline; Glaesmer, Heide; Hinz, Andreas; Zeynalova, Samira; Henger, Sylvia; Engel, Christoph et al.: What Builds Resilience? Sociodemographic and Social Correlates in the Population-Based LIFE-Adult-Study. International journal of environmental research and public health 19 (15). DOI: 10.3390/ijerph19159601. (source)

Wang, Song-Yau; Holzhey, Tanja; Heyn, Simone; Zehrfeld, Thomas; Fricke, Susann; Hoffmann, Franz Albert et al.: Impact of the changing landscape of induction therapy prior to autologous stem cell transplantation in 540 newly diagnosed myeloma patients: a retrospective real-world study. Journal of cancer research and clinical oncology. DOI: 10.1007/s00432-022-04184-x. (source)

Schirm, Sibylle; Haghikia, Arash; Brack, Markus; Ahnert, Peter; Nouailles, Geraldine; Suttorp, Norbert et al.: A biomathematical model of atherosclerosis in mice. PloS one 17 (8), e0272079. DOI: 10.1371/journal.pone.0272079. (source)

Ramdas, Shweta; Judd, Jonathan; Graham, Sarah E.; Kanoni, Stavroula; Wang, Yuxuan; Surakka, Ida et al.: A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Am J Hum Genet 109 (8), S. 1366–1387. DOI: 10.1016/j.ajhg.2022.06.012. (source)

Netto, Jeffrey; Teren, Andrej; Burkhardt, Ralph; Willenberg, Anja; Beutner, Frank; Henger, Sylvia et al.: Biomarkers for Non-Invasive Stratification of Coronary Artery Disease and Prognostic Impact on Long-Term Survival in Patients with Stable Coronary Heart Disease. Nutrients 14 (16). DOI: 10.3390/nu14163433. (source)

Lahti, Jari; Tuominen, Samuli; Yang, Qiong; Pergola, Giulio; Ahmad, Shahzad; Amin, Najaf et al.: Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning. Molecular psychiatry. DOI: 10.1038/s41380-022-01710-8. (source)

Kirsten, Toralf; Meineke, Frank; Löffler-Wirth, Henry; Uciteli, Alexandr; Beger, Christoph; Stäubert, Sebastian et al.: The Leipzig Health Atlas - An open platform to present, archive and share bio-medical data, analyses and models online. Methods of information in medicine. DOI: 10.1055/a-1914-1985. (source)

Al-Dabet, Moh'd Mohanad; Shahzad, Khurrum; Elwakiel, Ahmed; Sulaj, Alba; Kopf, Stefan; Bock, Fabian et al.: Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression. Nature communications 13 (1), S. 5062. DOI: 10.1038/s41467-022-32477-9. (source)

Struck, Manuel Florian; Kleber, Christian; Ewens, Sebastian; Ebel, Sebastian; Kirsten, Holger; Krämer, Sebastian et al.: Chest Tube Placement in Mechanically Ventilated Trauma Patients: Differences between Computed Tomography-Based Indication and Clinical Decision. Journal of clinical medicine 11 (14). DOI: 10.3390/jcm11144043. (source)

Pennitz, Peter; Kirsten, Holger; Friedrich, Vincent D.; Wyler, Emanuel; Goekeri, Cengiz; Obermayer, Benedikt et al.: A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics. European respiratory review : an official journal of the European Respiratory Society 31 (165). DOI: 10.1183/16000617.0056-2022. (source)

Kheifetz, Yuri; Kirsten, Holger; Scholz, Markus: On the Parametrization of Epidemiologic Models-Lessons from Modelling COVID-19 Epidemic. Viruses 14 (7). DOI: 10.3390/v14071468. (source)

Winkler, Thomas W.; Rasheed, Humaira; Teumer, Alexander; Gorski, Mathias; Rowan, Bryce X.; Stanzick, Kira J. et al.: Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Communications biology 5 (1), S. 580. DOI: 10.1038/s42003-022-03448-z. (source)

Vogelezang, Suzanne; Bradfield, Jonathan P.; Grant, Struan F. A.; Felix, Janine F.; Jaddoe, Vincent W. V.: Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes. BMC medical genomics 15 (1), S. 124. DOI: 10.1186/s12920-022-01281-1. (source)

Schillemans, Tessa; Tragante, Vinicius; Maitusong, Buamina; Gigante, Bruna; Cresci, Sharon; Laguzzi, Federica et al.: Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis. Frontiers in physiology 13, S. 909870. DOI: 10.3389/fphys.2022.909870. (source)

Klemp, Ireen; Hoffmann, Anne; Müller, Luise; Hagemann, Tobias; Horn, Kathrin; Rohde-Zimmermann, Kerstin et al.: DNA methylation patterns reflect individual's lifestyle independent of obesity. Clinical and translational medicine 12 (6), e851. DOI: 10.1002/ctm2.851. (source)

Gorski, Mathias; Rasheed, Humaira; Teumer, Alexander; Thomas, Laurent F.; Graham, Sarah E.; Sveinbjornsson, Gardar et al.: Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Kidney international. DOI: 10.1016/j.kint.2022.05.021. (source)

Begcevic Brkovic, Ilijana; Zöhrer, Benedikt; Scholz, Markus; Reinicke, Madlen; Dittrich, Julia; Kamalsada, Surab et al.: Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment. Nutrients 14 (12). DOI: 10.3390/nu14122474. (source)

Engel, Christoph; Wirkner, Kerstin; Zeynalova, Samira; Baber, Ronny; Binder, Hans; Ceglarek, Uta et al.: Cohort Profile: The LIFE-Adult-Study. International journal of epidemiology. DOI: 10.1093/ije/dyac114. (source)

Pott, Janne; Garcia, Tarcyane; Hauck, Stefanie M.; Petrera, Agnese; Wirkner, Kerstin; Loeffler, Markus et al.: Genetically regulated gene expression and proteins revealed discordant effects. PloS one 17 (5), e0268815. DOI: 10.1371/journal.pone.0268815. (source)

Toma, Augustin; Dos Santos, Claudia; Burzyńska, Beata; Góra, Monika; Kiliszek, Marek; Stickle, Natalie et al.: Diversity in the Expressed Genomic Host Response to Myocardial Infarction. Circulation research, 101161CIRCRESAHA121318391. DOI: 10.1161/CIRCRESAHA.121.318391. (source)

Dey Hazra, Rony-Orijit; Szewczyk, Karol; Ellwein, Alexander; Blach, Robert; Jensen, Gunnar; Kühnapfel, Andreas et al.: Minimum 2-year results of the second-generation CFR-PEEK locking plate on the proximal humeral fracture. European journal of orthopaedic surgery & traumatology. DOI: 10.1007/s00590-022-03298-9. (source)

Cheng, Wenke; Rosolowski, Maciej; Boettner, Julia; Desch, Steffen; Jobs, Alexander; Thiele, Holger; Buettner, Petra: High-density lipoprotein cholesterol efflux capacity and incidence of coronary artery disease and cardiovascular mortality: a systematic review and meta-analysis. Lipids in health and disease 21 (1), S. 47. DOI: 10.1186/s12944-022-01657-3. (source)

Rode, Michael; Nenoff, Kolja; Wirkner, Kerstin; Horn, Katrin; Teren, Andrej; Regenthal, Ralf et al.: Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers. PloS one 17 (4), e0266897. DOI: 10.1371/journal.pone.0266897. (source)

Landgraf, Kathrin; Kühnapfel, Andreas; Schlanstein, Maria; Biemann, Ronald; Isermann, Berend; Kempf, Elena et al.: Transcriptome Analyses of Adipose Tissue Samples Identify EGFL6 as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children. International journal of molecular sciences 23 (8). DOI: 10.3390/ijms23084349. (source)

Schmidt, Andreas W.; Kühnapfel, Andreas; Kirsten, Holger; Grallert, Harald; Hellerbrand, Claus; Kiefer, Falk et al.: Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms. Pancreatology. DOI: 10.1016/j.pan.2022.03.007. (source)

Luo, Ji; Brakel, Alexandra; Krizsan, Andor; Ludwig, Tobias; Mötzing, Marina; Volke, Daniela et al.: Sensitive and specific serological ELISA for the detection of SARS-CoV-2 infections. Virology journal 19 (1), S. 50. DOI: 10.1186/s12985-022-01768-4. (source)

Dam, Veerle; Onland-Moret, N. Charlotte; Burgess, Stephen; Chirlaque, Maria-Dolores; Peters, Sanne A. E.; Schuit, Ewoud et al.: Genetically determined reproductive aging and coronary heart disease: a bidirectional two-sample Mendelian Randomization. The Journal of clinical endocrinology and metabolism. DOI: 10.1210/clinem/dgac171. (source)

Thelwell, Michael; Bullas, Alice; Kühnapfel, Andreas; Hart, John; Ahnert, Peter; Wheat, Jon et al.: Modelling of human torso shape variation inferred by geometric morphometrics. PloS one 17 (3), e0265255. DOI: 10.1371/journal.pone.0265255. (source)

Rost, Franziska; Donaubauer, Bernd; Kirsten, Holger; Schwarz, Thomas; Zimmermann, Peter; Siekmeyer, Manuela et al.: Tracheal Tube Misplacement after Emergency Intubation in Pediatric Trauma Patients: A Retrospective, Exploratory Study. Children 9 (2). DOI: 10.3390/children9020289. (source)

Gohmann, Robin Fabian; Seitz, Patrick; Pawelka, Konrad; Majunke, Nicolas; Schug, Adrian; Heiser, Linda et al.: Combined Coronary CT-Angiography and TAVI Planning: Utility of CT-FFR in Patients with Morphologically Ruled-Out Obstructive Coronary Artery Disease. Journal of clinical medicine 11 (5). DOI: 10.3390/jcm11051331. (source)

Beuchel, Carl; Dittrich, Julia; Pott, Janne; Henger, Sylvia; Beutner, Frank; Isermann, Berend et al.: Whole Blood Metabolite Profiles Reflect Changes in Energy Metabolism in Heart Failure. Metabolites 12 (3). DOI: 10.3390/metabo12030216. (source)

Scholz, Markus; Horn, Katrin; Pott, Janne; Gross, Arnd; Kleber, Marcus E.; Delgado, Graciela E. et al.: Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis. Nature communications 13 (1). DOI: 10.1038/s41467-021-27706-6. (source)

Kühnapfel, Andreas; Horn, Katrin; Klotz, Ulrike; Kiehntopf, Michael; Rosolowski, Maciej; Loeffler, Markus et al.: Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia. Genes 13 (1). DOI: 10.3390/genes13010111. (source)

Kheifetz, Yuri; Scholz, Markus: Individual prediction of thrombocytopenia at next chemotherapy cycle - evaluation of dynamical model performances // Individual prediction of thrombocytopenia at next chemotherapy cycle: Evaluation of dynamic model performances. British journal of clinical pharmacology 87 (8), S. 3127–3138. DOI: 10.1111/bcp.14722. (source)

Graham, Sarah E.; Clarke, Shoa L.; Wu, Kuan-Han H.; Kanoni, Stavroula; Zajac, Greg J. M.; Ramdas, Shweta et al.: The power of genetic diversity in genome-wide association studies of lipids. Nature 600 (7890), S. 675–679. DOI: 10.1038/s41586-021-04064-3. (source)

Pott, Janne; Horn, Katrin; Zeidler, Robert; Kirsten, Holger; Ahnert, Peter; Kratzsch, Jürgen et al.: Sex-Specific Causal Relations between Steroid Hormones and Obesity-A Mendelian Randomization Study. Metabolites 11 (11). DOI: 10.3390/metabo11110738. (source)

Gohmann, Robin F.; Pawelka, Konrad; Seitz, Patrick; Majunke, Nicolas; Heiser, Linda; Renatus, Katharina et al.: Combined Coronary CT-Angiography and TAVR Planning for Ruling Out Significant Coronary Artery Disease: Added Value of Machine-Learning-Based CT-FFR. JACC. Cardiovascular imaging. DOI: 10.1016/j.jcmg.2021.09.013. (source)

Castaneda, Andy B.; Petty, Lauren E.; Scholz, Markus; Jansen, Rick; Weiss, Stefan; Zhang, Xiaoling et al.: Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues. Human molecular genetics. DOI: 10.1093/hmg/ddab236. (source)

Würfel, Marleen; Breitfeld, Jana; Gebhard, Claudia; Scholz, Markus; Baber, Ronny; Riedel-Heller, Steffi G. et al.: Interplay between adipose tissue secreted proteins, eating behavior and obesity. European journal of nutrition. DOI: 10.1007/s00394-021-02687-w. (source)

Vanhaverbeke, Maarten; Attard, Ritienne; Bartekova, Monika; Ben-Aicha, Soumaya; Brandenburger, Timo; Gonzalo-Calvo, David de et al.: Peripheral blood RNA biomarkers for cardiovascular disease from bench to bedside: A Position Paper from the EU-CardioRNA COST Action CA17129. Cardiovascular research. DOI: 10.1093/cvr/cvab327. (source)

Unterhuber, Matthias; Kresoja, Karl-Patrik; Rommel, Karl-Philipp; Besler, Christian; Baragetti, Andrea; Klöting, Nora et al.: Proteomics-Enabled Deep Learning Machine Algorithms Can Enhance Prediction of Mortality. J. Am. Coll. Cardiol. 78 (16), S. 1621–1631. DOI: 10.1016/j.jacc.2021.08.018. (source)

Ringel, Clemens; Dittrich, Julia; Gaudl, Alexander; Schellong, Paul; Beuchel, Carl Friedrich; Baber, Ronny et al.: Association of plasma trimethylamine N-oxide levels with atherosclerotic cardiovascular disease and factors of the metabolic syndrome. Atherosclerosis 335, S. 62–67. DOI: 10.1016/j.atherosclerosis.2021.09.026. (source)

Mentzel, Julia; Kynast, Tabea; Kohlmann, Johannes; Kirsten, Holger; Blüher, Matthias; Simon, Jan C. et al.: Reduced Serum Levels of Bone Formation Marker P1NP in Psoriasis. Frontiers in medicine 8, S. 730164. DOI: 10.3389/fmed.2021.730164. (source)

Gohmann, Robin F.; Temiz, Batuhan; Seitz, Patrick; Gottschling, Sebastian; Lücke, Christian; Krieghoff, Christian et al.: Segmentation and characterization of visceral and abdominal subcutaneous adipose tissue on CT with and without contrast medium: influence of 2D- and 3D-segmentation. Quantitative imaging in medicine and surgery 11 (10), S. 4258–4268. DOI: 10.21037/qims-21-178. (source)

Catanese, Silvia; Beuchel, Carl Friedrich; Sawall, Teresa; Lordick, Florian; Brauer, Rommy; Scholz, Markus et al.: Biomarkers related to fatty acid oxidative capacity are predictive for continued weight loss in cachectic cancer patients. Journal of cachexia, sarcopenia and muscle. DOI: 10.1002/jcsm.12817. (source)

Võsa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, Biao et al.: Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature genetics 53 (9), S. 1300–1310. DOI: 10.1038/s41588-021-00913-z. (source)

Pott, Janne; Gadin, Jesper; Theusch, Elizabeth; Kleber, Marcus E.; Delgado, Graciela E.; Kirsten, Holger et al.: Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2. Human molecular genetics. DOI: 10.1093/hmg/ddab279. (source)

Herta, Toni; Bhattacharyya, Aritra; Rosolowski, Maciej; Conrad, Claudia; Gurtner, Corinne; Gruber, Achim D. et al.: Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia. Frontiers in immunology 12, S. 726135. DOI: 10.3389/fimmu.2021.726135. (source)

Labus, Jakob; Winata, Johan; Schmidt, Torsten; Nicolai, Joachim; Uhlig, Christopher; Sveric, Kunislav et al.: Perioperative Two-Dimensional Left Ventricular Global Longitudinal Strain in Coronary Artery Bypass Surgery: A Prospective Observational Pilot Study. J. Cardiothorac. Vasc. Anesth. DOI: 10.1053/j.jvca.2021.08.004. (source)

Heyne, Guido; Ewens, Sebastian; Kirsten, Holger; Fakler, Johannes Karl Maria; Özkurtul, Orkun; Hempel, Gunther et al.: Risk factors and outcomes of unrecognised endobronchial intubation in major trauma patients. Emergency medicine journal : EMJ. DOI: 10.1136/emermed-2021-211786. (source)

Bracher, J.; Wolffram, D.; Deuschel, J.; Görgen, K.; Ketterer, J. L.; Ullrich, A. et al.: A pre-registered short-term forecasting study of COVID-19 in Germany and Poland during the second wave. Nature communications 12 (1), S. 5173. DOI: 10.1038/s41467-021-25207-0. (source)

Blume, Felix; Kirsten, Holger; Ahnert, Peter; Chakraborty, Trinad; Gross, Arnd; Horn, Katrin et al.: Verification of immunology-related genetic associations in BPD supports ABCA3 and five other genes. Pediatric research. DOI: 10.1038/s41390-021-01689-y. (source)

Kresoja, Karl-Patrik; Rommel, Karl-Philipp; Wachter, Rolf; Henger, Sylvia; Besler, Christian; Klöting, Nora et al.: Proteomics to Improve Phenotyping in Obese Patients with Heart Failure with Preserved Ejection Fraction. European journal of heart failure. DOI: 10.1002/ejhf.2291. (source)

Kempf, Elena; Vogel, Mandy; Vogel, Tim; Kratzsch, Jürgen; Landgraf, Kathrin; Kühnapfel, Andreas et al.: Dynamic alterations in linear growth and endocrine parameters in children with obesity and height reference values. EClinicalMedicine 37, S. 100977. DOI: 10.1016/j.eclinm.2021.100977. (source)

Huemer, Marie-Theres; Bauer, Alina; Petrera, Agnese; Scholz, Markus; Hauck, Stefanie M.; Drey, Michael et al.: Proteomic profiling of low muscle and high fat mass: a machine learning approach in the KORA S4/FF4 study. Journal of cachexia, sarcopenia and muscle. DOI: 10.1002/jcsm.12733. (source)

Wittekind, Dirk Alexander; Scholz, Markus; Kratzsch, Jürgen; Löffler, Markus; Horn, Katrin; Kirsten, Holger et al.: Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL. European journal of endocrinology. DOI: 10.1530/EJE-20-1220. (source)

Zeynalova, Samira; Bucksch, Karolin; Scholz, Markus; Yahiaoui-Doktor, Maryam; Gross, Melanie; Löffler, Markus et al.: Monocyte subtype counts are associated with 10-year cardiovascular disease risk as determined by the Framingham Risk Score among subjects of the LIFE-Adult study. PloS one 16 (3), e0247480. DOI: 10.1371/journal.pone.0247480. (source)

Schunk, Stefan J.; Kleber, Marcus E.; März, Winfried; Pang, Shichao; Zewinger, Stephen; Triem, Sarah et al.: Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur. Heart J. DOI: 10.1093/eurheartj/ehab107. (source)

Schmidt, Maria; Hopp, Lydia; Arakelyan, Arsen; Kirsten, Holger; Engel, Christoph; Wirkner, Kerstin et al.: The Human Blood Transcriptome in a Large Population Cohort and Its Relation to Aging and Health. Frontiers in big data 3, S. 548873. DOI: 10.3389/fdata.2020.548873. (source)

Epperlein, Sarah; Gebhardt, Claudia; Rohde, Kerstin; Chakaroun, Rima; Patt, Marie; Schamarek, Imke et al.: The Effect of FGF21 and Its Genetic Variants on Food and Drug Cravings, Adipokines and Metabolic Traits. Biomedicines 9 (4). DOI: 10.3390/biomedicines9040345. (source)

Beutner, Frank; Ritter, Christian; Scholz, Markus; Teren, Andrej; Holdt, Lesca Miriam; Teupser, Daniel et al.: A metabolomic approach to identify the link between sports activity and atheroprotection. European journal of preventive cardiology. DOI: 10.1093/eurjpc/zwaa122. (source)

Besler, Christian; Rommel, Karl-Philipp; Kresoja, Karl-Patrik; Mörbitz, Justus; Kirsten, Holger; Scholz, Markus et al.: Evaluation of phosphodiesterase 9A as a novel biomarker in heart failure with preserved ejection fraction. ESC heart failure. DOI: 10.1002/ehf2.13327. (source)

Schneider, Anne; Kirsten, Holger; Lordick, Franziska; Lordick, Florian; Lübbert, Christoph; Braun, Amrei von: Covid-19 in outpatients-Is fever a useful indicator for SARS-CoV-2 infection? PloS one 16 (2), e0246312. DOI: 10.1371/journal.pone.0246312. (source)

Kühnapfel, Andreas; Ahnert, Peter; Horn, Katrin; Kirsten, Holger; Loeffler, Markus; Scholz, Markus: First genome-wide association study of 99 body measures derived from 3-dimensional body scans. Genes & Diseases. DOI: 10.1016/j.gendis.2021.02.003. (source)

Hartiala, Jaana A.; Han, Yi; Jia, Qiong; Hilser, James R.; Huang, Pin; Gukasyan, Janet et al.: Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Eur. Heart J. 42 (9), S. 919–933. DOI: 10.1093/eurheartj/ehaa1040. (source)

Haak, Rainer; Brückner, Amelie; Häfer, Matthias; Scholz, Markus; Schneider, Hartmut: Is There an Association Between Clinical and SEM Quantitative Marginal Analysis in a 90-month Trial? The journal of adhesive dentistry 23 (1), S. 37–46. DOI: 10.3290/j.jad.b916821. (source)

Gohmann, Robin F.; Gottschling, Sebastian; Seitz, Patrick; Temiz, Batuhan; Krieghoff, Christian; Lücke, Christian et al.: 3D-segmentation and characterization of visceral and abdominal subcutaneous adipose tissue on CT: influence of contrast medium and contrast phase. Quantitative imaging in medicine and surgery 11 (2), S. 697–705. DOI: 10.21037/qims-20-907. (source)

Ceglarek, Uta; Schellong, Paul; Rosolowski, Maciej; Scholz, Markus; Willenberg, Anja; Kratzsch, Jürgen et al.: The novel cystatin C, lactate, interleukin-6, and N-terminal pro-B-type natriuretic peptide (CLIP)-based mortality risk score in cardiogenic shock after acute myocardial infarction. Eur. Heart J. DOI: 10.1093/eurheartj/ehab110. (source)

Kaddu-Mulindwa, Dominic; Rosolowski, Maciej; Ziepert, Marita; Regitz, Evi; Assmann, Gunter; Bewarder, Moritz et al.: VEGFR2 and VEGFA polymorphisms are not associated with an inferior prognosis in Caucasian patients with aggressive B-cell lymphoma. European journal of haematology 106 (1), S. 100–104. DOI: 10.1111/ejh.13526. (source)

Holzhey, Tanja; Pönisch, Wolfram; Wang, Song-Yau; Holzvogt, Madlen; Holzvogt, Bruno; Andrea, Marc et al.: Prognostic impact of rapid reduction of involved free light chains in multiple myeloma patients under first-line treatment with Bendamustine, Prednisone, and Bortezomib (BPV). Journal of cancer research and clinical oncology. DOI: 10.1007/s00432-020-03504-3. (source)

Schirm, Sibylle; Ahnert, Peter; Berger, Sarah; Nouailles, Geraldine; Wienhold, Sandra-Maria; Müller-Redetzky, Holger et al.: A biomathematical model of immune response and barrier function in mice with pneumococcal lung infection. PloS one 15 (12), e0243147. DOI: 10.1371/journal.pone.0243147. (source)

Pfeifle, Christian; Edel, Melanie; Schleifenbaum, Stefan; Kühnapfel, Andreas; Heyde, Christoph-Eckhard: The reliability of a restraint sensor system for the computer-supported detection of spinal stabilizing muscle deficiencies. BMC musculoskeletal disorders 21 (1), S. 597. DOI: 10.1186/s12891-020-03597-4. (source)

Kornej, Jelena; Scholz, Markus; Seewöster, Timm: Relationship between coronary artery disease and atrial fibrillation still unclear. Polish archives of internal medicine 130 (12), S. 1122–1123. DOI: 10.20452/pamw.15725. (source)

Huber, René; Augsten, Sandra; Kirsten, Holger; Zell, Roland; Stelzner, Axel; Thude, Hansjörg et al.: Identification of New, Functionally Relevant Mutations in the Coding Regions of the Human Fos and Jun Proto-Oncogenes in Rheumatoid Arthritis Synovial Tissue. Life 11 (1). DOI: 10.3390/life11010005. (source)

Gadi, Ihsan; Fatima, Sameen; Elwakiel, Ahmed; Nazir, Sumra; Al-Dabet, Mohd Mohanad; Rana, Rajiv et al.: Different DOACs Control Inflammation in Cardiac Ischemia-Reperfusion Differently. Circulation research. DOI: 10.1161/CIRCRESAHA.120.317219. (source)

Beuchel, Carl; Kirsten, Holger; Ceglarek, Uta; Scholz, Markus: Metabolite-Investigator: An integrated userfriendly workflow for metabolomics multi-study analysis. Bioinformatics (Oxford, England). DOI: 10.1093/bioinformatics/btaa967. (source)

Vogelezang, Suzanne; Bradfield, Jonathan P.; Ahluwalia, Tarunveer S.; Curtin, John A.; Lakka, Timo A.; Grarup, Niels et al.: Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLOS Genet. 16 (10), e1008718. DOI: 10.1371/journal.pgen.1008718. (source)

Skeide, Michael A.; Wehrmann, Katharina; Emami, Zahra; Kirsten, Holger; Hartmann, Annette M.; Rujescu, Dan: Neurobiological origins of individual differences in mathematical ability. PLoS biology 18 (10), e3000871. DOI: 10.1371/journal.pbio.3000871. (source)

Landgraf, Kathrin; Klöting, Nora; Gericke, Martin; Maixner, Nitzan; Guiu-Jurado, Esther; Scholz, Markus et al.: The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG. Cell reports 33 (3), S. 108295. DOI: 10.1016/j.celrep.2020.108295. (source)

Kornej, Jelena; Henger, Sylvia; Seewöster, Timm; Teren, Andrej; Burkhardt, Ralph; Thiele, Holger et al.: Prevalence of atrial fibrillation dependent on coronary artery status: Insights from the LIFE-Heart Study. Clinical cardiology. DOI: 10.1002/clc.23490. (source)

Gorski, Mathias; Jung, Bettina; Li, Yong; Matias-Garcia, Pamela R.; Wuttke, Matthias; Coassin, Stefan et al.: Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney international. DOI: 10.1016/j.kint.2020.09.030. (source)

Gialluisi, Alessandro; Andlauer, Till F. M.; Mirza-Schreiber, Nazanin; Moll, Kristina; Becker, Jessica; Hoffmann, Per et al.: Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia. Molecular psychiatry. DOI: 10.1038/s41380-020-00898-x. (source)

Beyer, Frauke; Zhang, Rui; Scholz, Markus; Wirkner, Kerstin; Loeffler, Markus; Stumvoll, Michael et al.: Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study. International journal of obesity. DOI: 10.1038/s41366-020-00702-4. (source)

Rosolowski, Maciej; Oberle, Volker; Ahnert, Peter; Creutz, Petra; Witzenrath, Martin; Kiehntopf, Michael et al.: Dynamics of cytokines, immune cell counts and disease severity in patients with community-acquired pneumonia - Unravelling potential causal relationships. Cytokine 136, S. 155263. DOI: 10.1016/j.cyto.2020.155263. (source)

Rosch, Sebastian; Rommel, Karl-Philipp; Scholz, Markus; Thiele, Holger; Lurz, Philipp: Transcriptomic Research in Heart Failure with Preserved Ejection Fraction: Current State and Future Perspectives. Cardiac failure review 6, e24. DOI: 10.15420/cfr.2019.19. (source)

Hofer, Edith; Roshchupkin, Gennady V.; Adams, Hieab H. H.; Knol, Maria J.; Lin, Honghuang; Li, Shuo et al.: Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature communications 11 (1), S. 4796. DOI: 10.1038/s41467-020-18367-y. (source)

Winkler, Thomas W.; Grassmann, Felix; Brandl, Caroline; Kiel, Christina; Günther, Felix; Strunz, Tobias et al.: Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease. BMC medical genomics 13 (1), S. 120. DOI: 10.1186/s12920-020-00760-7. (source)

Scholz, Markus; Henger, Sylvia; Beutner, Frank; Teren, Andrej; Baber, Ronny; Willenberg, Anja et al.: Cohort profile: The Leipzig Research Center for Civilization Diseases-Heart study (LIFE-Heart). International journal of epidemiology. DOI: 10.1093/ije/dyaa075. (source)

Rode, Michael; Teren, Andrej; Wirkner, Kerstin; Horn, Katrin; Kirsten, Holger; Loeffler, Markus et al.: Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure. PloS one 15 (8), e0237237. DOI: 10.1371/journal.pone.0237237. (source)

Kaune, Tom; Ruffert, Claudia; Hesselbarth, Nico; Damm, Marko; Krug, Sebastian; Cardinal von Widdern, Julian et al.: Analysis of GPRC6A variants in different pancreatitis etiologies. Pancreatology. DOI: 10.1016/j.pan.2020.08.001. (source)

Yuan, Fangcheng; Hung, Rayjean J.; Walsh, Naomi; Zhang, Han; Platz, Elizabeth A.; Wheeler, William et al.: Genome-wide association study data reveal genetic susceptibility to chronic inflammatory intestinal diseases and pancreatic ductal adenocarcinoma risk. Cancer research. DOI: 10.1158/0008-5472.CAN-20-0447. (source)

Wallenborn, Marco; Xu, Li-Xin; Kirsten, Holger; Rohani, Leili; Rudolf, Daniela; Ahnert, Peter et al.: Molecular analyses of glioblastoma stem-like cells and glioblastoma tissue. PloS one 15 (7), e0234986. DOI: 10.1371/journal.pone.0234986. (source)

Toenjes, Anke; Hoffmann, Annett; Kralisch, Susan; Qureshi, Abdul Rashid; Klöting, Nora; Scholz, Markus et al.: Pro-Neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease. European journal of endocrinology. DOI: 10.1530/EJE-20-0087. (source)

Teren, Andrej; Vogel, Anika; Beutner, Frank; Gielen, Stephan; Burkhardt, Ralph; Scholz, Markus et al.: Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease. Nutrition, metabolism, and cardiovascular diseases : NMCD. DOI: 10.1016/j.numecd.2020.05.031. (source)

Mahmoodi, Bakhtawar K.; Tragante, Vinicius; Kleber, Marcus E.; Holmes, Michael V.; Schmidt, Amand F.; McCubrey, Raymond O. et al.: Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data. Circulation. DOI: 10.1161/CIRCULATIONAHA.119.045526. (source)

Keller, Maria; Gebhardt, Claudia; Huth, Sandra; Schleinitz, Dorit; Heyne, Henrike; Scholz, Markus et al.: Genetically programmed changes in transcription of the novel progranulin regulator. J. Mol. Med. DOI: 10.1007/s00109-020-01942-7. (source)

Armstrong, Nicola J.; Mather, Karen A.; Sargurupremraj, Muralidharan; Knol, Maria J.; Malik, Rainer; Satizabal, Claudia L. et al.: Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke 51 (7), S. 2111–2121. DOI: 10.1161/STROKEAHA.119.027544. (source)

Schirm, Sibylle; Scholz, Markus: A biomathematical model of human erythropoiesis and iron metabolism. Scientific reports 10 (1), S. 8602. DOI: 10.1038/s41598-020-65313-5. (source)

Pott, Janne; Beutner, Frank; Horn, Katrin; Kirsten, Holger; Olischer, Kay; Wirkner, Kerstin et al.: Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. PloS one 15 (5), e0233728. DOI: 10.1371/journal.pone.0233728. (source)

Zheng, Yan; Huang, Tao; Wang, Tiange; Mei, Zhendong; Sun, Zhonghan; Zhang, Tao et al.: Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. European journal of epidemiology. DOI: 10.1007/s10654-020-00638-z. (source)

Hirschel, Josephin; Vogel, Mandy; Baber, Ronny; Garten, Antje; Beuchel, Carl; Dietz, Yvonne et al.: Relation of Whole Blood Amino Acid and Acylcarnitine Metabolome to Age, Sex, BMI, Puberty, and Metabolic Markers in Children and Adolescents. Metabolites 10 (4). DOI: 10.3390/metabo10040149. (source)

Ebert, Thomas; Gebhardt, Claudia; Scholz, Markus; Schleinitz, Dorit; Blüher, Matthias; Stumvoll, Michael et al.: Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status. Cytokine 131, S. 155088. DOI: 10.1016/j.cyto.2020.155088. (source)

Shin, Jean; Ma, Shaojie; Hofer, Edith; Patel, Yash; Vosberg, Daniel E.; Tilley, Steven et al.: Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cerebral cortex (New York, N.Y. : 1991). DOI: 10.1093/cercor/bhaa035. (source)

Przybilla, Jens; Ahnert, Peter; Bogatsch, Holger; Bloos, Frank; Brunkhorst, Frank M.; SepNet, Critical Care Trials Group et al.: Markov State Modelling of Disease Courses and Mortality Risks of Patients with Community-Acquired Pneumonia. Journal of clinical medicine 9 (2). DOI: 10.3390/jcm9020393. (source)

Müller-Redetzky, Holger; Kellermann, Ute; Wienhold, Sandra-Maria; Gutbier, Birgitt; Lienau, Jasmin; Hellwig, Katharina et al.: Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis. Anesthesiology. DOI: 10.1097/ALN.0000000000003149. (source)

Jacobi, Thomas; Massier, Lucas; Klöting, Nora; Horn, Katrin; Schuch, Alexander; Ahnert, Peter et al.: HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes. The Journal of clinical endocrinology and metabolism 105 (3). DOI: 10.1210/clinem/dgaa027. (source)

Hassenstein, Max J.; Aarabi, Ghazal; Ahnert, Peter; Becher, Heiko; Franzke, Claus-Werner; Fricke, Julia et al.: Selbst berichtete Infektionen in der NAKO Gesundheitsstudie – Einordnung in die gegenwärtige Forschungslandschaft. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 63 (4), S. 404–414. DOI: 10.1007/s00103-020-03114-x. (source)

Guillen-Guio, Beatriz; Lorenzo-Salazar, Jose M.; Ma, Shwu-Fan; Hou, Pei-Chi; Hernandez-Beeftink, Tamara; Corrales, Almudena et al.: Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study. The Lancet. Respiratory medicine 8 (3), S. 258–266. DOI: 10.1016/S2213-2600(19)30368-6. (source)

Duscha, Alexander; Gisevius, Barbara; Hirschberg, Sarah; Yissachar, Nissan; Stangl, Gabriele I.; Eilers, Eva et al.: Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism. Cell. DOI: 10.1016/j.cell.2020.02.035. (source)

Kuhl, Ulrike; Neef, Nicole E.; Kraft, Indra; Schaadt, Gesa; Dörr, Liane; Brauer, Jens et al.: The emergence of dyslexia in the developing brain. NeuroImage 211, S. 116633. DOI: 10.1016/j.neuroimage.2020.116633. (source)

Krämer, Sebastian; Broschewitz, Johannes; Kirsten, Holger; Sell, Carolin; Eichfeld, Uwe; Struck, Manuel Florian: Prognostic Factors for Iatrogenic Tracheal Rupture: A Single-Center Retrospective Cohort Study. Journal of clinical medicine 9 (2). DOI: 10.3390/jcm9020382. (source)

Hoffmann, Katja; Cazemier, Katja; Baldow, Christoph; Schuster, Silvio; Kheifetz, Yuri; Schirm, Sibylle et al.: Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology. BMC medical informatics and decision making 20 (1), S. 28. DOI: 10.1186/s12911-020-1039-x. (source)

Salazar, Manuela Gesell; Neugebauer, Sophie; Kacprowski, Tim; Michalik, Stephan; Ahnert, Peter; Creutz, Petra et al.: Association of proteome and metabolome signatures with severity in patients with community-acquired pneumonia. Journal of proteomics, S. 103627. DOI: 10.1016/j.jprot.2019.103627. (source)

Fietz, Simone A.; Namba, Takashi; Kirsten, Holger; Huttner, Wieland B.; Lachmann, Robert: Signs of reduced basal progenitor levels and cortical neurogenesis in human foetuses with open spina bifida at 11-15 weeks of gestation. The Journal of neuroscience. DOI: 10.1523/JNEUROSCI.0192-19.2019. (source)

Nauman, Ahmad T.; Teren, Andrej; Zeynalova, Samira; Thiery, Joachim; Regitz-Zagrosek, Vera; Scholz, Markus; Seeland, Ute: Nonobstructive Coronary Artery Disease at Angiography and Gender-Specific Indicators for Cardiovascular Events: 5-Year Follow-Up of the LIFE Heart Study. Journal of women's health (2002). DOI: 10.1089/jwh.2019.7730. (source)

Tin, Adrienne; Marten, Jonathan; Halperin Kuhns, Victoria L.; Li, Yong; Wuttke, Matthias; Kirsten, Holger et al.: Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature genetics. DOI: 10.1038/s41588-019-0504-x. (source)

Satizabal, Claudia L.; Adams, Hieab H. H.; Hibar, Derrek P.; White, Charles C.; Knol, Maria J.; Stein, Jason L. et al.: Genetic architecture of subcortical brain structures in 38,851 individuals. Nature genetics. DOI: 10.1038/s41588-019-0511-y. (source)

Kaune, Tom; Hollenbach, Marcus; Keil, Bettina; Chen, Jian-Min; Masson, Emmanuelle; Becker, Carla et al.: Common variants in glyoxalase I do not increase chronic pancreatitis risk. PloS one 14 (10), e0222927. DOI: 10.1371/journal.pone.0222927. (source)

Beuchel, Carl; Becker, Susen; Dittrich, Julia; Kirsten, Holger; Toenjes, Anke; Stumvoll, Michael et al.: Clinical and lifestyle related factors influencing whole blood metabolite levels - A comparative analysis of three large cohorts. Molecular Metabolism 29, S. 76-85. DOI: 10.1016/j.molmet.2019.08.010. (source)

Teumer, Alexander; Li, Yong; Ghasemi, Sahar; Prins, Bram P.; Wuttke, Matthias; Hermle, Tobias et al.: Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nature communications 10 (1), S. 4130. DOI: 10.1038/s41467-019-11576-0. (source)

Struck, Manuel Florian; Friedrich, Lars; Schleifenbaum, Stefan; Kirsten, Holger; Schummer, Wolfram; Winkler, Bernd E.: Effectiveness of different central venous catheter fixation suture techniques: An in vitro crossover study. PloS one 14 (9), e0222463. DOI: 10.1371/journal.pone.0222463. (source)

Pérez-Palma, Eduardo; Bustos, Bernabé I.; Lal, Dennis; Buch, Stephan; Azocar, Lorena; Toliat, Mohammad Reza et al.: Copy number variants in lipid metabolism genes are associated with gallstones disease in men. Eur. J. Hum. Genet. DOI: 10.1038/s41431-019-0501-7. (source)

Huang, Tao; Wang, Tiange; Zheng, Yan; Ellervik, Christina; Li, Xiang; Gao, Meng et al.: Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. JAMA network open 2 (9), e1910915. DOI: 10.1001/jamanetworkopen.2019.10915. (source)

Weingarten, Mark Florian Joachim; Scholz, Markus; Wohland, Tobias; Horn, Katrin; Stumvoll, Michael; Kovacs, Peter; Tönjes, Anke: Circulating oxytocin is genetically determined and associated with obesity and impaired glucose tolerance. The Journal of clinical endocrinology and metabolism. DOI: 10.1210/jc.2019-00643. (source)

Pfeifle, Isabelle; Bohnekamp, Jens; Volkhardt, Anna; Kirsten, Holger; Rohwedder, Astrid; Thum, Andreas et al.: MEK inhibitor cobimetinib rescues a dRaf mutant lethal phenotype in Drosophila melanogaster. Experimental dermatology. DOI: 10.1111/exd.14010. (source)

Wuttke, Matthias; Li, Yong; Li, Man; Sieber, Karsten B.; Feitosa, Mary F.; Gorski, Mathias et al.: A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nature genetics 51 (6), S. 957–972. DOI: 10.1038/s41588-019-0407-x. (source)

Wichmann, Gunnar; Gaede, Clara; Melzer, Susanne; Bocsi, Jozsef; Henger, Sylvia; Engel, Christoph et al.: Discrimination of Head and Neck Squamous Cell Carcinoma Patients and Healthy Adults by 10-Color Flow Cytometry: Development of a Score Based on Leukocyte Subsets. Cancers 11 (6). DOI: 10.3390/cancers11060814. (source)

Schuldt, Anna-Livia; Kirsten, Holger; Tuennemann, Jan; Heindl, Mario; van Bommel, Florian; Feisthammel, Juergen et al.: Necessity of transnasal gastroscopy in routine diagnostics: a patient-centred requirement analysis. BMJ open gastroenterology 6 (1), e000264. DOI: 10.1136/bmjgast-2018-000264. (source)

Pott, Janne; Bae, Yoon Ju; Horn, Katrin; Teren, Andrej; Kühnapfel, Andreas; Kirsten, Holger et al.: Genetic association study of eight steroid hormones and implications for sexual dimorphism of coronary artery disease. The Journal of clinical endocrinology and metabolism. DOI: 10.1210/jc.2019-00757. (source)

Patel, Riyaz; Tragante, Vinicius; Schmidt, Amand F.; McCubrey, Raymond O.; Holmes, Michael V.; Howe, Laurence J. et al.: Subsequent Event Risk in Individuals with Established Coronary Heart Disease: Design and Rationale of the GENIUS-CHD Consortium. Circulation. Genomic and precision medicine. DOI: 10.1161/CIRCGEN.119.002470. (source)

Sander, Caroline; Wallenborn, Marco; Brandt, Vivian Pascal; Ahnert, Peter; Reuschel, Vera; Eisenlöffel, Christan et al.: Central neurocytoma: SNP array analyses, subtel FISH, and review of the literature. Pathol. Res. Pract. DOI: 10.1016/j.prp.2019.03.025. (source)

Ahnert, Peter; Creutz, Petra; Horn, Katrin; Schwarzenberger, Fabian; Kiehntopf, Michael; Hossain, Hamid et al.: Sequential organ failure assessment score is an excellent operationalization of disease severity of adult patients with hospitalized community acquired pneumonia - results from the prospective observational PROGRESS study. Crit Care 23 (1), S. 110. DOI: 10.1186/s13054-019-2316-x. (source)

Patel, Riyaz S.; Schmidt, Amand F.; Tragante, Vinicius; McCubrey, Raymond O.; Holmes, Michael V.; Howe, Laurence J. et al.: Association of Chromosome 9p21 with Subsequent Coronary Heart Disease Events: A GENIUS-CHD Study of Individual Participant Data. Circulation. Genomic and precision medicine. DOI: 10.1161/CIRCGEN.119.002471. (source)

Kheifetz, Yuri; Scholz, Markus: Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy. PLoS computational biology 15 (3), e1006775. DOI: 10.1371/journal.pcbi.1006775. (source)

Huber, René; Kirsten, Holger; Näkki, Annu; Pohlers, Dirk; Thude, Hansjörg; Eidner, Thorsten et al.: Association of Human FOS Promoter Variants with the Occurrence of Knee-Osteoarthritis in a Case Control Association Study. International journal of molecular sciences 20 (6). DOI: 10.3390/ijms20061382. (source)

Gomes, Clarissa Pedrosa da C.; Ágg, Bence; Andova, Andrejaana; Arslan, Serdal; Baker, Andrew; Barteková, Monika et al.: Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129. Non-coding RNA 5 (2). DOI: 10.3390/ncrna5020031. (source)

Breitfeld, Jana; Wiele, Norman; Gutsmann, Beate; Stumvoll, Michael; Blüher, Matthias; Scholz, Markus et al.: Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans. Lipids. DOI: 10.1002/lipd.12139. (source)

Franceschini, Nora; Giambartolomei, Claudia; Vries, Paul S. de; Finan, Chris; Bis, Joshua C.; Huntley, Rachael P. et al.: GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature communications 9 (1), S. 5141. DOI: 10.1038/s41467-018-07340-5. (source)

Dittrich, Julia; Beutner, Frank; Teren, Andrej; Thiery, Joachim; Burkhardt, Ralph; Scholz, Markus; Ceglarek, Uta: Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease. Atherosclerosis 281, S. 17–24. DOI: 10.1016/j.atherosclerosis.2018.11.006. (source)

Walker, Christopher J.; Oakes, Christopher C.; Genutis, Luke K.; Giacopelli, Brian; Liyanarachchi, Sandya; Nicolet, Deedra et al.: Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA. Leukemia. DOI: 10.1038/s41375-018-0281-z. (source)

Vojinovic, Dina; Adams, Hieab H.; Jian, Xueqiu; Yang, Qiong; Smith, Albert Vernon; Bis, Joshua C. et al.: Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nature communications 9 (1), S. 3945. DOI: 10.1038/s41467-018-06234-w. (source)

Schneider, H.; Steigerwald-Otremba, A. S.; Häfer, M.; Krause, F.; Scholz, M.; Haak, R.: Is Optical Coherence Tomography a Potential Tool to Evaluate Marginal Adaptation of Class III/IV Composite Restorations In Vivo? Operative dentistry. DOI: 10.2341/17-192-C. (source)

Ondruschka, Benjamin; Woydt, Lina; Bernhard, Michael; Franke, Heike; Kirsten, Holger; Löffler, Sabine et al.: Post-mortem in situ stability of serum markers of cerebral damage and acute phase response. International journal of legal medicine. DOI: 10.1007/s00414-018-1925-2. (source)

Woydt, Lina; Bernhard, Michael; Kirsten, Holger; Burkhardt, Ralph; Hammer, Niels; Gries, André et al.: Intra-individual alterations of serum markers routinely used in forensic pathology depending on increasing post-mortem interval. Scientific reports 8 (1), S. 12811. DOI: 10.1038/s41598-018-31252-5. (source)

Lalem, Torkia; Zhang, Lu; Scholz, Markus; Burkhardt, Ralph; Saccheti, Victoria; Teren, Andrej et al.: Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction. International journal of cardiology. DOI: 10.1016/j.ijcard.2018.07.042. (source)

Wallenborn, M.; Petters, O.; Rudolf, D.; Hantmann, H.; Richter, M.; Ahnert, P. et al.: Comprehensive high-resolution genomic profiling and cytogenetics of human chondrocyte cultures by GTG-banding, locus-specific FISH, SKY and SNP array. European cells & materials 35, S. 225–241. DOI: 10.22203/eCM.v035a16. (source)

Weiss, Frank Ulrich; Hesselbarth, Nico; Párniczky, Andrea; Mosztbacher, Dora; Lämmerhirt, Felix; Ruffert, Claudia et al.: Common variants in the CLDN2-MORC4 and PRSS1-PRSS2 loci confer susceptibility to acute pancreatitis. Pancreatology (Pancreatology : official journal of the International Association of Pancreatology (IAP) … [et al.]). DOI: 10.1016/j.pan.2018.05.486. (source)

Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David et al.: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature communications 9 (1), S. 2098. DOI: 10.1038/s41467-018-04362-x. (source)

Pott, Janne; Schlegel, Valentin; Teren, Andrej; Horn, Katrin; Kirsten, Holger; Bluecher, Christina et al.: Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. Circulation. Genomic and precision medicine 11 (5), S. e001992. DOI: 10.1161/CIRCGEN.117.001992. (source)

Ondruschka, Benjamin; Sieber, Monique; Kirsten, Holger; Franke, Heike; Dressler, Jan: Measurement of cerebral biomarkers proving traumatic brain injuries in post-mortem body fluids. Journal of neurotrauma. DOI: 10.1089/neu.2017.5441. (source)

Jawinski, Philippe; Kirsten, Holger; Sander, Christian; Spada, Janek; Ulke, Christine; Huang, Jue et al.: Human brain arousal in the resting state: a genome-wide association study. Molecular psychiatry. DOI: 10.1038/s41380-018-0052-2. (source)

Baumgart, Pia; Kirsten, Holger; Haak, Rainer; Olms, Constanze: Biomechanical properties of polymer-infiltrated ceramic crowns on one-piece zirconia implants after long-term chewing simulation. International journal of implant dentistry 4 (1), S. 16. DOI: 10.1186/s40729-018-0127-5. (source)

Baier, Daniel; Teren, Andrej; Wirkner, Kerstin; Loeffler, Markus; Scholz, Markus: Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult. Clin Res Cardiol. DOI: 10.1007/s00392-018-1278-3. (source)

Müller, Bent; Boltze, Johannes; Czepezauer, Ivonne; Hesse, Volker; Wilcke, Arndt; Kirsten, Holger: Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1. Genetics and molecular biology. DOI: 10.1590/1678-4685-GMB-2017-0165. (source)

Gutbier, Birgitt; Neuhauß, Anne-Kathrin; Reppe, Katrin; Ehrler, Carolin; Santel, Ansgar; Kaufmann, Jörg et al.: Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia. American journal of respiratory and critical care medicine. DOI: 10.1164/rccm.201708-1733OC. (source)

Ebert, Thomas; Gebhardt, Claudia; Scholz, Markus; Wohland, Tobias; Schleinitz, Dorit; Fasshauer, Mathias et al.: Relationship between twelve adipocytokines and distinct components of the metabolic syndrome. The Journal of clinical endocrinology and metabolism. DOI: 10.1210/jc.2017-02085. (source)

Tönjes, Anke; Scholz, Markus; Krüger, Jacqueline; Krause, Kerstin; Schleinitz, Dorit; Kirsten, Holger et al.: Genome wide meta-analysis identifies novel determinants of circulating serum progranulin. Human molecular genetics. DOI: 10.1093/hmg/ddx413. (source)

Thiele, Alena G.; Gausche, Ruth; Lindenberg, Cornelia; Beger, Christoph; Arelin, Maria; Rohde, Carmen et al.: Growth and Final Height Among Children With Phenylketonuria. Pediatrics 140 (5). DOI: 10.1542/peds.2017-0015. (source)

Gross, Arnd; Tönjes, Anke; Scholz, Markus: On the impact of relatedness on SNP association analysis. BMC Genet. 18 (1), S. 104. DOI: 10.1186/s12863-017-0571-x. (source)

Schirm, Sibylle; Engel, Christoph; Loibl, Sibylle; Loeffler, Markus; Scholz, Markus: Model-based optimization of G-CSF treatment during cytotoxic chemotherapy. Journal of cancer research and clinical oncology. DOI: 10.1007/s00432-017-2540-1. (source)

Freiermuth, David; Mets, Berend; Bolliger, Daniel; Reuthebuch, Oliver; Doebele, Thomas; Scholz, Markus et al.: Sevoflurane and Isoflurane-Pharmacokinetics, Hemodynamic Stability and Cardio-protective Effects During Cardiopulmonary Bypass. Journal of cardiothoracic and vascular anesthesia 31 (6), S. e85-e86. DOI: 10.1053/j.jvca.2016.10.010. (source)

Zeller, Tanja; Seiffert, Moritz; Müller, Christian; Scholz, Markus; Schäffer, Anna; Ojeda, Francisco et al.: Genome-Wide Association Analysis for Severity of Coronary Artery Disease Using the Gensini Scoring System. Frontiers in cardiovascular medicine 4, S. 57. DOI: 10.3389/fcvm.2017.00057. (source)

Remmler, Johannes; Schneider, Christoph; Treuner-Kaueroff, Theresa; Bartels, Michael; Seehofer, Daniel; Scholz, Markus et al.: Increased Level of Interleukin 6 Associates With Increased 90-day and 1-year Mortality in Patients With End-stage Liver Disease. Clinical gastroenterology and hepatology (Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association). DOI: 10.1016/j.cgh.2017.09.017. (source)

Oak, Prajakta; Pritzke, Tina; Thiel, Isabella; Koschlig, Markus; Mous, Daphne S.; Windhorst, Anita et al.: Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease. EMBO molecular medicine. DOI: 10.15252/emmm.201607308. (source)

Müller, Bent; Schaadt, Gesa; Boltze, Johannes; Emmrich, Frank; Skeide, Michael A.; Neef, Nicole E. et al.: ATP2C2 and DYX1C1 are putative modulators of dyslexia-related MMR. Brain Behav 7 (11), S. e00851. DOI: 10.1002/brb3.851. (source)

Lukowski, Samuel W.; Lloyd-Jones, Luke R.; Holloway, Alexander; Kirsten, Holger; Hemani, Gibran; Yang, Jian et al.: Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood. Nature communications 8 (1), S. 483. DOI: 10.1038/s41467-017-00473-z. (source)

Buchmann, Nikolaus; Scholz, Markus; Lill, Christina M.; Burkhardt, Ralph; Eckardt, Rahel; Norman, Kristina et al.: Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin. Acta diabetologica. DOI: 10.1007/s00592-017-1036-4. (source)

Mayer, Tanja; Bolliger, Daniel; Scholz, Markus; Reuthebuch, Oliver; Gregor, Michael; Meier, Patrick et al.: Urine Biomarkers of Tubular Renal Cell Damage for the Prediction of Acute Kidney Injury After Cardiac Surgery-A Pilot Study. Journal of cardiothoracic and vascular anesthesia. DOI: 10.1053/j.jvca.2017.04.024. (source)

Rosendahl, Jonas; Kirsten, Holger; Hegyi, Eszter; Kovacs, Peter; Weiss, Frank Ulrich; Laumen, Helmut et al.: Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. DOI: 10.1136/gutjnl-2017-314454. (source)

Zewinger, Stephen; Kleber, Marcus E.; Tragante, Vinicius; McCubrey, Raymond O.; Schmidt, Amand F.; Direk, Kenan et al.: Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. The lancet. Diabetes & endocrinology 5 (7), S. 534–543. DOI: 10.1016/S2213-8587(17)30096-7. (source)

Kaiser, Thorsten; Kinny-Köster, Benedict; Bartels, Michael; Berg, Thomas; Scholz, Markus; Engelmann, Cornelius et al.: Cholesterol esterification in plasma as a biomarker for liver function and prediction of mortality. BMC gastroenterology 17 (1), S. 57. DOI: 10.1186/s12876-017-0614-9. (source)

Pott, Janne; Burkhardt, Ralph; Beutner, Frank; Horn, Katrin; Teren, Andrej; Kirsten, Holger et al.: Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. Atherosclerosis 259, S. 32–40. DOI: 10.1016/j.atherosclerosis.2017.02.018. (source)

Glock, Fabian; Scholz, Markus; Kuehnapfel, Andreas; Kiess, Wieland: Validity and reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents-response to the rebuttal by Sabour. Pediatric research. DOI: 10.1038/pr.2017.76. (source)

Becker, Susen; Kinny-Koster, Benedict; Bartels, Michael; Scholz, Markus; Seehofer, Daniel; Berg, Thomas et al.: Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. PloS one 12 (3), S. e0174424. DOI: 10.1371/journal.pone.0174424. (source)

Teren, A.; Kirsten, H.; Beutner, F.; Scholz, M.; Holdt, L. M.; Teupser, D. et al.: Alteration of Multiple Leukocyte Gene Expression Networks is Linked with Magnetic Resonance Markers of Prognosis After Acute ST-Elevation Myocardial Infarction. Scientific reports 7, S. 41705. DOI: 10.1038/srep41705. (source)

Neef, Nicole E.; Müller, Bent; Liebig, Johanna; Schaadt, Gesa; Grigutsch, Maren; Gunter, Thomas C. et al.: Dyslexia risk gene relates to representation of sound in the auditory brainstem. Developmental cognitive neuroscience 24, S. 63–71. DOI: 10.1016/j.dcn.2017.01.008. (source)

Kuehnapfel, Andreas; Schwarzenberger, Fabian; Scholz, Markus: On the Conditional Power in Survival Time Analysis Considering Cure Fractions. The international journal of biostatistics. DOI: 10.1515/ijb-2015-0073. (source)

Kuehnapfel, Andreas; Ahnert, Peter; Loeffler, Markus; Scholz, Markus: Body surface assessment with 3D laser-based anthropometry: reliability, validation, and improvement of empirical surface formulae. European journal of applied physiology 117 (2), S. 371–380. DOI: 10.1007/s00421-016-3525-5. (source)

Glock, Fabian; Vogel, Mandy; Naumann, Stephanie; Kuehnapfel, Andreas; Scholz, Markus; Hiemisch, Andreas et al.: Validity and intraobserver reliability of three-dimensional scanning compared with conventional anthropometry for children and adolescents from a population-based cohort study. Pediatric research 81 (5), S. 736–744. DOI: 10.1038/pr.2016.274. (source)

Kraft, Indra; Schreiber, Jan; Cafiero, Riccardo; Metere, Riccardo; Schaadt, Gesa; Brauer, Jens et al.: Predicting early signs of dyslexia at a preliterate age by combining behavioral assessment with structural MRI. NeuroImage 143, S. 378–386. DOI: 10.1016/j.neuroimage.2016.09.004. (source)

Treudler, R.; Walther, F.; Ahnert, P.; Simon, J-C: Unerwünschte Arzneimittelreaktionen beim älteren Menschen. Erste Daten aus dem Leipziger Forschungszentrum für Zivilisationserkrankungen (LIFE). Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 68 (1), S. 5–11. DOI: 10.1007/s00105-016-3897-9. (source)

Roshyara, Nab Raj; Horn, Katrin; Kirsten, Holger; Ahnert, Peter; Scholz, Markus: Comparing performance of modern genotype imputation methods in different ethnicities. Scientific reports 6, S. 34386. DOI: 10.1038/srep34386. (source)

Loley, Christina; Alver, Maris; Assimes, Themistocles L.; Bjonnes, Andrew; Goel, Anuj; Gustafsson, Stefan et al.: No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Scientific reports 6, S. 35278. DOI: 10.1038/srep35278. (source)

Vausort, Melanie; Salgado-Somoza, Antonio; Zhang, Lu; Leszek, Przemyslaw; Scholz, Markus; Teren, Andrej et al.: Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction. Journal of the American College of Cardiology 68 (11), S. 1247–1248. DOI: 10.1016/j.jacc.2016.06.040. (source)

Scherag, Andre; Schoneweck, Franziska; Kesselmeier, Miriam; Taudien, Stefan; Platzer, Matthias; Felder, Marius et al.: Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. EBioMedicine 12, S. 239–246. DOI: 10.1016/j.ebiom.2016.08.043. (source)

Landgraf, Kathrin; Scholz, Markus; Kovacs, Peter; Kiess, Wieland; Körner, Antje: FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children? PloS one 11 (8), S. e0161739. DOI: 10.1371/journal.pone.0161739. (source)

Holdt, Lesca M.; Stahringer, Anika; Sass, Kristina; Pichler, Garwin; Kulak, Nils A.; Wilfert, Wolfgang et al.: Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans. Nature communications 7, S. 12429. DOI: 10.1038/ncomms12429. (source)

Hasenclever, Dirk; Scholz, Markus: Comparing Measures of Association in 2x2 Probability Tables. The Open Statistics 7 (1), S. 20–35. DOI: 10.2174/1876527001607010020. (source)

Skeide, Michael A.; Kraft, Indra; Muller, Bent; Schaadt, Gesa; Neef, Nicole E.; Brauer, Jens et al.: NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school. Brain (Brain : a journal of neurology) 139 (Pt 10), S. 2792–2803. DOI: 10.1093/brain/aww153. (source)

Rösch, Katja; Scholz, Markus; Hasenclever, Dirk: Modeling combined chemo- and immunotherapy of high-grade non-Hodgkin lymphoma. Leukemia & lymphoma 57 (7), S. 1697–1708. DOI: 10.3109/10428194.2015.1110746. (source)

Löffler-Wirth, Henry; Willscher, Edith; Ahnert, Peter; Wirkner, Kerstin; Engel, Christoph; Loeffler, Markus; Binder, Hans: Novel Anthropometry Based on 3D-Bodyscans Applied to a Large Population Based Cohort. PloS one 11 (7), S. e0159887. DOI: 10.1371/journal.pone.0159887. (source)

Kinny-Köster, Benedict; Bartels, Michael; Becker, Susen; Scholz, Markus; Thiery, Joachim; Ceglarek, Uta; Kaiser, Thorsten: Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver Disease. PloS one 11 (7), S. e0159205. DOI: 10.1371/journal.pone.0159205. (source)

Freiermuth, David; Mets, Berend; Bolliger, Daniel; Reuthebuch, Oliver; Doebele, Thomas; Scholz, Markus et al.: Sevoflurane and Isoflurane-Pharmacokinetics, Hemodynamic Stability, and Cardioprotective Effects During Cardiopulmonary Bypass. Journal of cardiothoracic and vascular anesthesia 30 (6), S. 1494–1501. DOI: 10.1053/j.jvca.2016.07.011. (source)

Ahnert, Peter; Creutz, Petra; Scholz, Markus; Schütte, Hartwig; Engel, Christoph; Hossain, Hamid et al.: PROGRESS - prospective observational study on hospitalized community acquired pneumonia. BMC pulmonary medicine 16 (1), S. 108. DOI: 10.1186/s12890-016-0255-8. (source)

Müller, Bent; Wilcke, Arndt; Czepezauer, Ivonne; Ahnert, Peter; Boltze, Johannes; Kirsten, Holger: Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort. Scientific reports 6, S. 27901. DOI: 10.1038/srep27901. (source)

Schirm, Sibylle; Ahnert, Peter; Wienhold, Sandra; Mueller-Redetzky, Holger; Nouailles-Kursar, Geraldine; Loeffler, Markus et al.: A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice. PloS one 11 (5), S. e0156047. DOI: 10.1371/journal.pone.0156047. (source)

Kuehnapfel, Andreas; Ahnert, Peter; Loeffler, Markus; Broda, Anja; Scholz, Markus: Reliability of 3D laser-based anthropometry and comparison with classical anthropometry. Scientific reports 6, S. 26672. DOI: 10.1038/srep26672. (source)

Jawinski, Philippe; Tegelkamp, Sophie; Sander, Christian; Hantzsch, Madlen; Huang, Jue; Mauche, Nicole et al.: Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep. Chronobiology international 33 (7), S. 1–13. DOI: 10.1080/07420528.2016.1178275. (source)

Spada, Janek; Scholz, Markus; Kirsten, Holger; Hensch, Tilman; Horn, Katrin; Jawinski, Philippe et al.: Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study. Journal of sleep research 25 (6), S. 690–701. DOI: 10.1111/jsr.12421. (source)

Teren, Andrej; Beutner, Frank; Wirkner, Kerstin; Löffler, Markus; Scholz, Markus: Relationship Between Determinants of Arterial Stiffness Assessed by Diastolic and Suprasystolic Pulse Oscillometry: Comparison of Vicorder and Vascular Explorer. Medicine 95 (10), S. e2963. DOI: 10.1097/MD.0000000000002963. (source)

Wilcke, Arndt; Müller, Bent; Schaadt, Gesa; Kirsten, Holger; Boltze, Johannes: High acceptance of an early dyslexia screening test involving genetic analyses in Germany. Eur. J. Hum. Genet. 24 (2), S. 178–182. DOI: 10.1038/ejhg.2015.103. (source)

Weissgerber, Alexander; Scholz, Markus; Teren, Andrej; Sandri, Marcus; Teupser, Daniel; Gielen, Stephan et al.: The value of noncoronary atherosclerosis for identifying coronary artery disease: results of the Leipzig LIFE Heart Study. Clin Res Cardiol 105 (2), S. 172–181. DOI: 10.1007/s00392-015-0900-x. (source)

Peschka, A.; Berger, Th; Maier, Th; Scholz, M.; Lüth, T. C.; Strauß, G.: Evaluation eines Mikromanipulators für die Mittelohrchirurgie: Eine präklinische Studie. Laryngo- rhino- otologie 95 (2), S. 112–117. DOI: 10.1055/s-0034-1398658. (source)

Müller, Bent; Wilcke, Arndt; Boulesteix, Anne-Laure; Brauer, Jens; Passarge, Eberhard; Boltze, Johannes; Kirsten, Holger: Improved prediction of complex diseases by common genetic markers: state of the art and further perspectives. Human genetics 135 (3), S. 259–272. DOI: 10.1007/s00439-016-1636-z. (source)

Ebert, T.; Kralisch, S.; Wurst, U.; Scholz, M.; Stumvoll, M.; Kovacs, P. et al.: Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations. International journal of obesity 40 (2), S. 260–265. DOI: 10.1038/ijo.2015.157. (source)

Kirsten, Holger; Scholz, Markus; Kovacs, Peter; Grallert, Harald; Peters, Annette; Strauch, Konstantin et al.: Genetic variants of lipase activity in chronic pancreatitis. Gut 65 (1), S. 184–185. DOI: 10.1136/gutjnl-2015-309521. (source)

Waseem, Zakhary; Lindner, Jacob; Sgouropoulou, Sophia; Eibel, Sarah; Probst, Stefan; Scholz, Markus; Ender, Joerg: Independent Risk Factors for Fast-Track Failure Using a Predefined Fast-Track Protocol in Preselected Cardiac Surgery Patients. Journal of cardiothoracic and vascular anesthesia 29 (6), S. 1461–1465. DOI: 10.1053/j.jvca.2015.05.193. (source)

Jawinski, Philippe; Sander, Christian; Mauche, Nicole; Spada, Janek; Huang, Jue; Schmidt, Anna et al.: Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles. Neuropsychobiology 72 (2), S. 65–73. DOI: 10.1159/000437438. (source)

Skeide, Michael A.; Kirsten, Holger; Kraft, Indra; Schaadt, Gesa; Müller, Bent; Neef, Nicole et al.: Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children. NeuroImage 118, S. 414–421. DOI: 10.1016/j.neuroimage.2015.06.024. (source)

CARDIoGRAMplusC4D Consortium: A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature genetics 47 (10), S. 1121–1130. DOI: 10.1038/ng.3396. (source)

Burkhardt, Ralph; Kirsten, Holger; Beutner, Frank; Holdt, Lesca M.; Gross, Arnd; Teren, Andrej et al.: Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood. PLOS Genet. 11 (9), S. e1005510. DOI: 10.1371/journal.pgen.1005510. (source)

Breitling, Clara; Gross, Arnd; Büttner, Petra; Weise, Sebastian; Schleinitz, Dorit; Kiess, Wieland et al.: Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children. PloS one 10 (9), S. e0138064. DOI: 10.1371/journal.pone.0138064. (source)

Ronke, Claudius; Dannemann, Michael; Halbwax, Michel; Fischer, Anne; Helmschrodt, Christin; Brügel, Mathias et al.: Lineage-Specific Changes in Biomarkers in Great Apes and Humans. PloS one 10 (8), S. e0134548. DOI: 10.1371/journal.pone.0134548. (source)

Roshyara, Nab Raj; Scholz, Markus: Impact of genetic similarity on imputation accuracy. BMC Genet. 16, S. 90. DOI: 10.1186/s12863-015-0248-2. (source)

Männel, Claudia; Meyer, Lars; Wilcke, Arndt; Boltze, Johannes; Kirsten, Holger; Friederici, Angela D.: Working-memory endophenotype and dyslexia-associated genetic variant predict dyslexia phenotype. Cortex 71, S. 291–305. DOI: 10.1016/j.cortex.2015.06.029. (source)

Loeffler, Markus; Engel, Christoph; Ahnert, Peter; Alfermann, Dorothee; Arelin, Katrin; Baber, Ronny et al.: The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany. BMC public health 15 (1), S. 691. DOI: 10.1186/s12889-015-1983-z. (source)

Wichmann, Gunnar; Rosolowski, Maciej; Krohn, Knut; Kreuz, Markus; Boehm, Andreas; Reiche, Anett et al.: The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer. International journal of cancer 137 (12), S. 2846–2857. DOI: 10.1002/ijc.29649. (source)

Nitzsche, Björn; Frey, Stephen; Collins, Louis D.; Seeger, Johannes; Lobsien, Donald; Dreyer, Antje et al.: A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes. Frontiers in neuroanatomy 9, S. 69. DOI: 10.3389/fnana.2015.00069. (source)

Kirsten, Holger; Al-Hasani, Hoor; Holdt, Lesca; Gross, Arnd; Beutner, Frank; Krohn, Knut et al.: Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†. Human molecular genetics 24 (16), S. 4746–4763. DOI: 10.1093/hmg/ddv194. (source)

Hass, Johanna; Walton, Esther; Wright, Carrie; Beyer, Andreas; Scholz, Markus; Turner, Jessica et al.: Associations between DNA methylation and schizophrenia-related intermediate phenotypes - a gene set enrichment analysis. Progress in neuro-psychopharmacology & biological psychiatry 59, S. 31–39. DOI: 10.1016/j.pnpbp.2015.01.006. (source)

Boehm, A.; Lindner, F.; Wichmann, G.; Bauer, U.; Wittekind, Christian; Knoedler, M. et al.: Impact of indication-shift of primary and adjuvant chemo radiation in advanced laryngeal and hypopharyngeal squamous cell carcinoma. Eur Arch Otorhinolaryngol 272 (8), S. 2017–2025. DOI: 10.1007/s00405-014-3134-z. (source)

Schöneweck, F.; Kuhnt, E.; Scholz, M.; Brunkhorst, F. M.; Scherag, A.: Common genomic variation in the FER gene: useful to stratify patients with sepsis due to pneumonia? Intensive care medicine 41 (7), S. 1379–1381. DOI: 10.1007/s00134-015-3829-7. (source)

Mathias, Daniel; Mitchel, Ronald E J; Barclay, Mirela; Wyatt, Heather; Bugden, Michelle; Priest, Nicholas D. et al.: Low-Dose Irradiation Affects Expression of Inflammatory Markers in the Heart of ApoE -/- Mice. PloS one 10 (3), S. e0119661. DOI: 10.1371/journal.pone.0119661. (source)

Liu, Xuanshi; Hinney, Anke; Scholz, Markus; Scherag, André; Tönjes, Anke; Stumvoll, Michael et al.: Indications for potential parent-of-origin effects within the FTO gene. PloS one 10 (3), S. e0119206. DOI: 10.1371/journal.pone.0119206. (source)

Fjeld, Karianne; Weiss, Frank Ulrich; Lasher, Denise; Rosendahl, Jonas; Chen, Jian-Min; Johansson, Bente B. et al.: A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nature genetics 47 (5), S. 518–522. DOI: 10.1038/ng.3249. (source)

Xu, Li-Xin; Holland, Heidrun; Kirsten, Holger; Ahnert, Peter; Krupp, Wolfgang; Bauer, Manfred et al.: Three gangliogliomas: Results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature. Neuropathology (Neuropathology : official journal of the Japanese Society of Neuropathology) 35 (2), S. 148–157. DOI: 10.1111/neup.12176. (source)

Kraft, Indra; Cafiero, Riccardo; Schaadt, Gesa; Brauer, Jens; Neef, Nicole E.; Müller, Bent et al.: Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers. Brain (Brain : a journal of neurology) 138 (Pt 9), S. e378. DOI: 10.1093/brain/awv036. (source)

Hass, Johanna; Walton, Esther; Kirsten, Holger; Turner, Jessica; Wolthusen, Rick; Roessner, Veit et al.: Complexin2 modulates working memory-related neural activity in patients with schizophrenia. European archives of psychiatry and clinical neuroscience 265 (2), S. 137–145. DOI: 10.1007/s00406-014-0550-4. (source)

Derikx, Monique H.; Kovacs, Peter; Scholz, Markus; Masson, Emmanuelle; Chen, Jian-Min; Ruffert, Claudia et al.: Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut 64 (9), S. 1426–1433. DOI: 10.1136/gutjnl-2014-307453. (source)

Berger, T.; Kaiser, T.; Scholz, M.; Bachmann, A.; Ceglarek, U.; Hesse, G. et al.: Fibrinogen is not a prognostic factor for response to HELP-apheresis in sudden sensorineural hearing loss (SSHL). European archives of oto-rhino-laryngology (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery) 272 (12), S. 3693–3703. DOI: 10.1007/s00405-014-3449-9. (source)

Köberle, Margarethe; Müller, Kristin; Kamprad, Manja; Horn, Friedemann; Scholz, Markus: Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging. Molecular imaging 14, S. 400–413. (source)

Tönjes, Anke; Scholz, Markus; Breitfeld, Jana; Marzi, Carola; Grallert, Harald; Gross, Arnd et al.: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLOS Genet. 10 (12), S. e1004854. DOI: 10.1371/journal.pgen.1004854. (source)

Schirm, Sibylle; Engel, Christoph; Loeffler, Markus; Scholz, Markus: Modelling chemotherapy effects on granulopoiesis. BMC Syst Biol 8 (1), S. 138. DOI: 10.1186/s12918-014-0138-7. (source)

Walton, Esther; Liu, Jingyu; Hass, Johanna; White, Tonya; Scholz, Markus; Roessner, Veit et al.: MB-COMT promoter DNA methylation is associated with working-memory processing in schizophrenia patients and healthy controls. Epigenetics 9 (8), S. 1101–1107. DOI: 10.4161/epi.29223. (source)

Roshyara, Nab Raj; Kirsten, Holger; Horn, Katrin; Ahnert, Peter; Scholz, Markus: Impact of pre-imputation SNP-filtering on genotype imputation results. BMC Genet. 15 (1), S. 88. DOI: 10.1186/s12863-014-0088-5. (source)

Probst, Stefan; Cech, Christof; Haentschel, Dirk; Scholz, Markus; Ender, Joerg: A specialized post anaesthetic care unit improves fast-track management in cardiac surgery: a prospective randomized trial. Crit Care 18 (4), S. 468. DOI: 10.1186/s13054-014-0468-2. (source)

Burkhardt, Jana; Blume, Mechthild; Petit-Teixeira, Elisabeth; Hugo Teixeira, Vitor; Steiner, Anke; Quente, Elfi et al.: Cellular Adhesion Gene SELP Is Associated with Rheumatoid Arthritis and Displays Differential Allelic Expression // Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression. PloS one 9 (8), S. e103872. DOI: 10.1371/journal.pone.0103872. (source)

Roshyara, Nab Raj; Scholz, Markus: fcGENE: a versatile tool for processing and transforming SNP datasets. PloS one 9 (7), S. e97589. DOI: 10.1371/journal.pone.0097589. (source)

Gross, Arnd; Schirm, Sibylle; Scholz, Markus: Ycasd - a tool for capturing and scaling data from graphical representations. BMC Bioinformatics 15, S. 219. DOI: 10.1186/1471-2105-15-219. (source)

Flehmig, Gesine; Scholz, Markus; Klöting, Nora; Fasshauer, Mathias; Tönjes, Anke; Stumvoll, Michael et al.: Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation. PloS one 9 (6), S. e99785. DOI: 10.1371/journal.pone.0099785. (source)

Schirm, Sibylle; Engel, Christoph; Loeffler, Markus; Scholz, Markus: A combined model of human erythropoiesis and granulopoiesis under growth factor and chemotherapy treatment. Theor Biol Med Model 11, S. 24. DOI: 10.1186/1742-4682-11-24. (source)

Mueller, B.; Ahnert, P.; Burkhardt, J.; Brauer, J.; Czepezauer, I.; Quente, E. et al.: Genetic risk variants for dyslexia on chromosome 18 in a German cohort. Genes Brain Behav. 13 (3), S. 350–356. DOI: 10.1111/gbb.12118. (source)

Hackermüller, Jörg; Reiche, Kristin; Otto, Christian; Hösler, Nadine; Blumert, Conny; Brocke-Heidrich, Katja et al.: Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs. Genome Biol. 15 (3), S. R48. DOI: 10.1186/gb-2014-15-3-r48. (source)

Roesch, Katja; Hasenclever, Dirk; Scholz, Markus: Modelling lymphoma therapy and outcome. Bulletin of mathematical biology 76 (2), S. 401–430. DOI: 10.1007/s11538-013-9925-3. (source)

Eszlinger, Markus; Krogdahl, Annelise; Münz, Sina; Rehfeld, Christian; Precht Jensen, Eva Magrethe; Ferraz, Carolina et al.: Impact of molecular screening for point mutations and rearrangements in routine air-dried fine-needle aspiration samples of thyroid nodules. Thyroid 24 (2), S. 305–313. DOI: 10.1089/thy.2013.0278. (source)

Spada, Janek; Sander, Christian; Burkhardt, Ralph; Häntzsch, Madlen; Mergl, Roland; Scholz, Markus et al.: Genetic association of objective sleep phenotypes with a functional polymorphism in the neuropeptide S receptor gene. PloS one 9 (6), S. e98789. DOI: 10.1371/journal.pone.0098789. (source)

Zeynalova, S.; Ziepert, Marita; Scholz, Markus; Schirm, Sibylle; Zwick, C.; Pfreundschuh, M.; Loeffler, Markus: Comparison and modelling of pegylated or unpegylated G-CSF schedules in CHOP-14 regimen of elderly patients with aggressive B-cell lymphoma. Ann. Hematol. 92 (12), S. 1641–1652. DOI: 10.1007/s00277-013-1842-x. (source)

Wienhold, Romy; Scholz, Markus; Adler, Jürgen-Bernhard; Günster, Christian; Paschke, Ralf: The management of thyroid nodules: a retrospective analysis of health insurance data. Dtsch Arztebl Int 110 (49), S. 827–834. DOI: 10.3238/arztebl.2013.0827. (source)

Krinner, Axel; Roeder, Ingo; Loeffler, Markus; Scholz, Markus: Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis. BMC Syst Biol 7, S. 117. DOI: 10.1186/1752-0509-7-117. (source)

Holmes, Michael V.; Simon, Tabassome; Exeter, Holly J.; Folkersen, Lasse; Asselbergs, Folkert W.; Guardiola, Montse et al.: Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J. Am. Coll. Cardiol. 62 (21), S. 1966–1976. DOI: 10.1016/j.jacc.2013.06.044. (source)

Breitfeld, Jana; Heiker, John T.; Böttcher, Yvonne; Schleinitz, Dorit; Tönjes, Anke; Weidle, Kerstin et al.: Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels. J. Mol. Med. 91 (11), S. 1285–1292. DOI: 10.1007/s00109-013-1062-9. (source)

Teren, Andrej; Beutner, Frank; Wirkner, Kerstin; Loeffler, Markus; Scholz, Markus: Validity, intra- and inter-observer reliability of automated devices for the assessment of ankle brachial index using photo-plethysmography. BMC Cardiovasc Disord 13, S. 81. DOI: 10.1186/1471-2261-13-81. (source)

Rehak, Matus; Spies, E.; Scholz, Markus; Wiedemann, Peter: Behandlung der Patienten mit einem Venenastverschluss in Abhängigkeit von der Verschlussdauer. Ophthalmologe 110 (10), S. 966–974. DOI: 10.1007/s00347-012-2723-8. (source)

Penk, Anja; Förster, Yvonne; Scheidt, Holger A.; Nimptsch, Ariane; Hacker, Michael C.; Schulz-Siegmund, Michaela et al.: The pore size of PLGA bone implants determines the de novo formation of bone tissue in tibial head defects in rats. Magn Reson Med 70 (4), S. 925–935. DOI: 10.1002/mrm.24541. (source)

Holland, Heidrun; Xu, Li-Xin; Ahnert, Peter; Kirsten, Holger; Koschny, Ronald; Bauer, Manfred et al.: Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma. Pathol. Res. Pract. 209 (9), S. 541–547. DOI: 10.1016/j.prp.2013.06.001. (source)

Gast, Marie-Therese; Tönjes, Anke; Keller, Maria; Horstmann, Annette; Steinle, Nanette; Scholz, Markus et al.: The role of rs2237781 within GRM8 in eating behavior. Brain Behav 3 (5), S. 495–502. DOI: 10.1002/brb3.151. (source)

Holdt, Lesca Miriam; Hoffmann, Steve; Sass, Kristina; Langenberger, David; Scholz, Markus; Krohn, Knut et al.: Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks. PLOS Genet. 9 (7), S. e1003588. DOI: 10.1371/journal.pgen.1003588. (source)

Barkholt, Lisbeth; Flory, Egbert; Jekerle, Veronika; Lucas-Samuel, Sophie; Ahnert, Peter; Bisset, Louise et al.: Risk of tumorigenicity in mesenchymal stromal cell-based therapies--bridging scientific observations and regulatory viewpoints. Cytotherapy 15 (7), S. 753–759. DOI: 10.1016/j.jcyt.2013.03.005. (source)

Aust, Gabriela; Kerner, Christiane; Gonsior, Susann; Sittig, Doreen; Schneider, Hartmut; Buske, Peter et al.: Mice overexpressing CD97 in intestinal epithelial cells provide a unique model for mammalian postnatal intestinal cylindrical growth. Mol. Biol. Cell 24 (14), S. 2256–2268. DOI: 10.1091/mbc.E13-04-0175. (source)

Schirm, Sibylle; Engel, Christoph; Loeffler, Markus; Scholz, Markus: A biomathematical model of human erythropoiesis under erythropoietin and chemotherapy administration. PloS one 8 (6), S. e65630. DOI: 10.1371/journal.pone.0065630. (source)

Hass, Johanna; Walton, Esther; Kirsten, Holger; Liu, Jingyu; Priebe, Lutz; Wolf, Christiane et al.: A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype. PloS one 8 (6), S. e64872. DOI: 10.1371/journal.pone.0064872. (source)

Müller, M. K.; Ludewig, E.; Oechtering, G.; Scholz, Markus; Flegel, T.: The vacuum phenomenon in intervertebral disc disease of dogs based on computed tomography images. J Small Anim Pract 54 (5), S. 253–257. DOI: 10.1111/jsap.12063. (source)

Thomas, Stephanie; Kratzsch, Dorothea; Schaab, Michael; Scholz, Markus; Grunewald, Sonja; Thiery, Joachim et al.: Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa. Fertil. Steril. 99 (5), S. 1256. DOI: 10.1016/j.fertnstert.2012.12.022. (source)

Hasenclever, Dirk; Scholz, Markus: Comparing measures of association in 2x2 probability tables. arXiv:1302.6161v1. Online verfügbar unter http://arxiv-web3.library.cornell.edu/pdf/1302.6161v1.pdf, zuletzt geprüft am 22.07.2014. (source)

Burkhardt, Jana; Kirsten, Holger; Holland, Heidrun; Krupp, Wolfgang; Ligges, Carolin; Quente, Elfi et al.: Association of rs2069459 in the CDK5 gene with dyslexia in a German cohort. Psychiatr. Genet. 22 (6), S. 307–308. DOI: 10.1097/YPG.0b013e328353aeae. (source)

Scholz, Markus: Biomathematische Modellierung von Therapiewirkungen bei Lymphomerkrankungen - Ein Beitrag zur Medizinischen Systembiologie. Habilitation. Universität Leipzig (kein Review). Online verfügbar unter http://www.qucosa.de/fileadmin/data/qucosa/documents/10141/habil_scholz_pflicht.pdf, zuletzt geprüft am 21.07.2014. (source)

Beutner, Frank; Teren, Andrej; Gielen, Stephan; Schuler, Gerhard; Wirkner, Kerstin; Tiller, Daniel et al.: Automated photoplethysmography-based determination of ankle-brachial index: a validation study against Doppler sonography. Clin Res Cardiol 101 (11), S. 875–883. DOI: 10.1007/s00392-012-0471-z. (source)

Ender, A.; Eibel, S.; Hasheminejad, E.; Scholz, Markus; Kaisers, Udo X.; Mukherjee, Chirojit; Ender, Joerg: \"Real-time-3-dimensional-full-volume\"-datensatz. Nutzen in der problemfokussierten intraoperativen transösophagealen echokardiographie. Anaesthesist 61 (10), S. 875–882. DOI: 10.1007/s00101-012-2088-z. (source)

Wagner, Daniel-Christoph; Bojko, Mitja; Peters, Myriam; Lorenz, Marlene; Voigt, Cornelia; Kaminski, Alexander et al.: Impact of age on the efficacy of bone marrow mononuclear cell transplantation in experimental stroke. Exp Transl Stroke Med 4 (1), S. 17. DOI: 10.1186/2040-7378-4-17. (source)

Kirsten, Holger; Wilcke, Arndt; Ligges, Carolin; Boltze, Johannes; Ahnert, Peter: Association study of a functional genetic variant in KIAA0319 in German dyslexics. Psychiatr. Genet. 22 (4), S. 216–217. DOI: 10.1097/YPG.0b013e32834c0c97. (source)

Scholz, Markus; Schirm, Sibylle; Wetzler, Marcus; Engel, Christoph; Loeffler, Markus: Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans. Theor Biol Med Model 9, S. 32. DOI: 10.1186/1742-4682-9-32. (source)

Burkhardt, Jana; Kirsten, Holger; Wolfram, Grit; Quente, Elfi; Ahnert, Peter: Differential allelic expression of IL13 and CSF2 genes associated with asthma. Genet. Mol. Biol. 35 (3), S. 567–574. DOI: 10.1590/S1415-47572012005000055. (source)

Holland, Heidrun; Ahnert, Peter; Koschny, Ronald; Kirsten, Holger; Bauer, Manfred; Schober, Ralf et al.: Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locus-specific FISH, and high density SNP-array. Pathol. Res. Pract. 208 (6), S. 325–330. DOI: 10.1016/j.prp.2012.03.010. (source)

Gross, Arnd; Ziepert, Marita; Scholz, Markus: KMWin--a convenient tool for graphical presentation of results from Kaplan-Meier survival time analysis. PloS one 7 (6), S. e38960. DOI: 10.1371/journal.pone.0038960. (source)

Fischer, Janett; Böhm, Stephan; Scholz, Markus; Müller, Tobias; Witt, Heiko; George, Jacob et al.: Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection. Hepatology 55 (6), S. 1700–1710. DOI: 10.1002/hep.25582. (source)

Glauche, Ingmar; Horn, Katrin; Horn, Matthias; Thielecke, Lars; Essers, M A G; Trumpp, Andreas; Roeder, Ingo: Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations. Br. J. Cancer 106 (11), S. 1742–1752. DOI: 10.1038/bjc.2012.142. (source)

Mukherjee, Chirojit; Koch, Eva; Banusch, Joergen; Scholz, Markus; Kaisers, Udo X.; Ender, Joerg: Intrathecal morphine is superior to intravenous PCA in patients undergoing minimally invasive cardiac surgery. Ann Card Anaesth 15 (2), S. 122–127. DOI: 10.4103/0971-9784.95075. (source)

Mukherjee, Chirojit; Groeger, Steffen; Hogan, Maurice; Scholz, Markus; Kaisers, Udo X.; Ender, Joerg: Pre-operative Tei Index does not predict left ventricular function immediately after mitral valve repair. Ann Card Anaesth 15 (2), S. 111–117. DOI: 10.4103/0971-9784.95073. (source)

Wilcke, Arndt; Ligges, Carolin; Burkhardt, Jana; Alexander, Michael; Wolf, Christiane; Quente, Elfi et al.: Imaging genetics of FOXP2 in dyslexia. Eur. J. Hum. Genet. 20 (2), S. 224–229. DOI: 10.1038/ejhg.2011.160. (source)

Maier, Thomas; Strauss, Gero; Scholz, Markus; Berger, Thomas; Kielhorn, Anne; Entsfellner, Konrad et al.: A new evaluation and training system for micro-telemanipulation at the middle ear. Conf Proc IEEE Eng Med Biol Soc 2012, S. 932–935. DOI: 10.1109/EMBC.2012.6346085. (source)

Beutner, Frank; Teupser, Daniel; Gielen, Stephan; Holdt, Lesca Miriam; Scholz, Markus; Boudriot, Enno et al.: Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease. PloS one 6 (12), S. e29070. DOI: 10.1371/journal.pone.0029070. (source)

Scholz, Markus; Kirsten, Holger: Comparison of scoring methods for the detection of causal genes with or without rare variants. BMC Proc 5 Suppl 9, S. S49. DOI: 10.1186/1753-6561-5-S9-S49. (source)

Holland, Heidrun; Mocker, Kristin; Ahnert, Peter; Kirsten, Holger; Hantmann, Helene; Koschny, Ronald et al.: High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas. Cancer Genet 204 (10), S. 541–549. DOI: 10.1016/j.cancergen.2011.10.007. (source)

Veeramah, Krishna R.; Tönjes, Anke; Kovacs, Peter; Gross, Arnd; Wegmann, Daniel; Geary, Patrick et al.: Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur. J. Hum. Genet. 19 (9), S. 995–1001. DOI: 10.1038/ejhg.2011.65. (source)

Müller, Anne; Scholz, Markus; Blankenstein, Oliver; Binder, Gerhard; Pfäffle, Roland; Körner, Antje et al.: Harmonization of growth hormone measurements with different immunoassays by data adjustment. Clin. Chem. Lab. Med. 49 (7), S. 1135–1142. DOI: 10.1515/CCLM.2011.201. (source)

Gross, Arnd; Tönjes, Anke; Kovacs, Peter; Veeramah, Krishna R.; Ahnert, Peter; Roshyara, Nab R. et al.: Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays. BMC Genet. 12, S. 67. DOI: 10.1186/1471-2156-12-67. (source)

Grey, Daniel; Sack, Ulrich; Scholz, Markus; Knaack, Heike; Fricke, Stephan; Oppel, Christoph et al.: Increased CD64 expression on polymorphonuclear neutrophils indicates infectious complications following solid organ transplantation. Cytometry A 79 (6), S. 446–460. DOI: 10.1002/cyto.a.21049. (source)

Aust, Gabriela; Uptaite-Patapoviene, Migle; Scholz, Markus; Richter, Olaf; Rohm, Silvio; Blüher, Matthias: Circulating Nampt and RBP4 levels in patients with carotid stenosis undergoing carotid endarterectomy (CEA). Clin. Chim. Acta 412 (13-14), S. 1195–1200. DOI: 10.1016/j.cca.2011.03.008. (source)

Holland, Heidrun; Livrea, Michela; Ahnert, Peter; Koschny, Ronald; Kirsten, Holger; Meixensberger, Jürgen et al.: Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis. Pathol. Res. Pract. 207 (5), S. 310–316. DOI: 10.1016/j.prp.2010.12.010. (source)

Scholz, Markus; Engert, A.; Franklin, J.; Josting, A.; Diehl, V.; Hasenclever, Dirk; Loeffler, Markus: Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. Ann. Oncol. 22 (3), S. 681–688. DOI: 10.1093/annonc/mdq408. (source)

Lange, T.; Hubmann, M.; Burkhardt, Ralph; Franke, G-N; Cross, M.; Scholz, Markus et al.: Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning. Leukemia 25 (3), S. 498–505. DOI: 10.1038/leu.2010.283. (source)

Jahns, Jutta; Anderegg, Ulf; Saalbach, Anja; Rosin, Britt; Patties, Ina; Glasow, Annegret et al.: Influence of low dose irradiation on differentiation, maturation and T-cell activation of human dendritic cells. Mutat. Res. 709-710, S. 32–39. DOI: 10.1016/j.mrfmmm.2011.02.007. (source)

Mocker, Kristin; Holland, Heidrun; Ahnert, Peter; Schober, Ralf; Bauer, Manfred; Kirsten, Holger et al.: Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics. Pathol. Res. Pract. 207 (1), S. 67–72. DOI: 10.1016/j.prp.2010.09.001. (source)

Dänzer, Stefan; Freitag, Stefan; Beyersdorff, Dirk; Scholz, Markus; Burgert, Oliver; Stolzenburg, Jens-Uwe: Segmentierung der Prostata aus MRT-Bilddaten mittels eines statistischen Modells. Bildverarbeitung für die Medizin, S. 114–118. DOI: 10.1007/978-3-642-19335-4_25. (source)

Wess, Christian; Sarnthein, Johannes; Krayenbühl, Niklaus; Scholz, Markus; Kunze, Ekkehard; Meixensberger, Jürgen: Spectral iEEG markers precede SSEP events during surgery for subarachnoid hemorrhage. Clin Neurophysiol 121 (12), S. 2172–2176. DOI: 10.1016/j.clinph.2010.04.031. (source)

Holland, Heidrun; Koschny, Thomas; Ahnert, Peter; Meixensberger, Jürgen; Koschny, Ronald: WHO grade-specific comparative genomic hybridization pattern of astrocytoma - a meta-analysis. Pathol. Res. Pract. 206 (10), S. 663–668. DOI: 10.1016/j.prp.2010.04.002. (source)

Teupser, Daniel; Baber, Ronny; Ceglarek, Uta; Scholz, Markus; Illig, Thomas; Gieger, Christian et al.: Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ Cardiovasc Genet 3 (4), S. 331–339. DOI: 10.1161/CIRCGENETICS.109.907873. (source)

Walther, Thomas; Schuler, Gerhard; Borger, Michael Andrew; Kempfert, Joerg; Seeburger, Jörg; Rückert, Yvonne et al.: Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement. Eur. Heart J. 31 (11), S. 1398–1403. DOI: 10.1093/eurheartj/ehq060. (source)

Scholz, Markus; Gross, Arnd; Loeffler, Markus: A biomathematical model of human thrombopoiesis under chemotherapy. Journal of Theoretical Biology 264 (2), S. 287–300. DOI: 10.1016/j.jtbi.2009.12.032. (source)

Koschny, Ronald; Holland, Heidrun; Sykora, Jaromir; Erdal, Hande; Krupp, Wolfgang; Bauer, Manfred et al.: Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis. J. Neurooncol. 97 (2), S. 171–185. DOI: 10.1007/s11060-009-0010-6. (source)

Holdt, Lesca Miriam; Beutner, Frank; Scholz, Markus; Gielen, Stephan; Gäbel, Gábor; Bergert, Hendrik et al.: ANRIL expression is associated with atherosclerosis risk at chromosome 9p21. Arterioscler. Thromb. Vasc. Biol. 30 (3), S. 620–627. DOI: 10.1161/ATVBAHA.109.196832. (source)

Kranz, Alexander; Wagner, Daniel-Christoph; Kamprad, Manja; Scholz, Markus; Schmidt, Uwe Richard; Nitzsche, Franziska et al.: Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats. Brain Res. 1315, S. 128–136. DOI: 10.1016/j.brainres.2009.12.001. (source)

Scholz, Markus; Hasenclever, Dirk: Comparison of estimators for measures of linkage disequilibrium. Int J Biostat 6 (1), S. 1. (source)

López Herráez, David; Bauchet, Marc; Tang, Kun; Theunert, Christoph; Pugach, Irina; Li, Jing et al.: Genetic variation and recent positive selection in worldwide human populations: evidence from nearly 1 million SNPs. PloS one 4 (11), S. e7888. DOI: 10.1371/journal.pone.0007888. (source)

Burkhardt, Jana; Petit-Teixeira, Elisabeth; Teixeira, Vitor Hugo; Kirsten, Holger; Garnier, Sophie; Ruehle, Sandra et al.: Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. J. Rheumatol. 36 (10), S. 2149–2157. DOI: 10.3899/jrheum.090059. (source)

Scholz, Markus; Engel, Christoph; Apt, D.; Sankar, S. L.; Goldstein, E.; Loeffler, Markus: Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats. Cell Prolif. 42 (6), S. 823–837. DOI: 10.1111/j.1365-2184.2009.00641.x. (source)

Scholz, Markus; Ackermann, Manuela; Engel, Christoph; Emmrich, Frank; Loeffler, Markus; Kamprad, Manja: A pharmacokinetic model of filgrastim and pegfilgrastim application in normal mice and those with cyclophosphamide-induced granulocytopaenia. Cell Prolif. 42 (6), S. 813–822. DOI: 10.1111/j.1365-2184.2009.00638.x. (source)

Scholz, Markus; Ackermann, Manuela; Emmrich, Frank; Loeffler, Markus; Kamprad, Manja: Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastim schedules in a chemotherapy mouse model. Biologics 3, S. 27–37. (source)

Wilcke, Arndt; Weissfuss, Jana; Kirsten, Holger; Wolfram, Grit; Boltze, Johannes; Ahnert, Peter: The role of gene DCDC2 in German dyslexics. Ann Dyslexia 59 (1), S. 1–11. DOI: 10.1007/s11881-008-0020-7. (source)

Fassl, Jens; Walther, Thomas; Groesdonk, Heinrich Volker; Kempfert, Joerg; Borger, Michael Andrew; Scholz, Markus et al.: Anesthesia management for transapical transcatheter aortic valve implantation: a case series. J. Cardiothorac. Vasc. Anesth. 23 (3), S. 286–291. DOI: 10.1053/j.jvca.2008.12.026. (source)

Rehak, Matus; Müller, M.; Scholz, Markus; Wiercinska, J.; Niederwieser, D.; Wiedemann, Peter: Antiphospholipidsyndrom und retinale venöse Verschlüsse. Metaanalyse publizierter Studien. Ophthalmologe 106 (5), S. 427–434. DOI: 10.1007/s00347-008-1811-2. (source)

Kirsten, Holger; Petit-Teixeira, Elisabeth; Scholz, Markus; Hasenclever, Dirk; Hantmann, Helene; Heider, Dirk et al.: Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res. Ther. 11 (3), S. R60. DOI: 10.1186/ar2683. (source)

Kirsten, Holger; Petit-Teixeira, Elisabeth; Hantmann, Helene; Reichardt, J.; Burkhardt, Jana; Emmrich, Frank et al.: A family-based study does not support the association of a functional polymorphism in the gene for endothelial nitric oxide synthase with risk for rheumatoid arthritis. Scand. J. Rheumatol. 38 (4), S. 320–321. DOI: 10.1080/03009740802668547. (source)

Kirsten, Holger; Burkhardt, Jana; Hantmann, Helene; Hunzelmann, Nico; Vaith, Peter; Ahnert, Peter; Melchers, Inga: 5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population. Arthritis Res. Ther. 11 (2), S. 403. DOI: 10.1186/ar2606. (source)

Häntschel, D.; Fassl, Jens; Scholz, Markus; Sommer, Marcus; Funkat, Anne-Kathrin; Wittmann, M.; Ender, Joerg: Leipziger "Fast-track"-Protokoll in der Kardioanästhesie. Effektiv, sicher und ökonomisch sinnvoll. Anaesthesist 58 (4), S. 379–386. DOI: 10.1007/s00101-009-1508-1. (source)

Jaen, Olivier; Petit-Teixeira, Elisabeth; Kirsten, Holger; Ahnert, Peter; Semerano, Luca; Pierlot, Céline et al.: No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis. Arthritis Res. Ther. 11 (1), S. R5. DOI: 10.1186/ar2589. (source)

Melchers, Inga; Ahnert, Peter: Zur Bedeutung der Genvariante PTPN22 620W für die Rheumatologie. Z Rheumatol 67 (7), S. 593–595. DOI: 10.1007/s00393-008-0381-7. (source)

Reich, Doreen M.; Hau, Susann; Stahl, Tobias; Scholz, Markus; Naumann, Wilfried; Emmrich, Frank et al.: Neuronal hypoxia in vitro: investigation of therapeutic principles of HUCB-MNC and CD133+ stem cells. BMC Neurosci 9, S. 91. DOI: 10.1186/1471-2202-9-91. (source)

Krupp, Wolfgang; Holland, Heidrun; Koschny, Ronald; Bauer, Manfred; Schober, Ralf; Kirsten, Holger et al.: Genome-wide genetic characterization of an atypical meningioma by single-nucleotide polymorphism array-based mapping and classical cytogenetics. Cancer Genet. Cytogenet. 184 (2), S. 87–93. DOI: 10.1016/j.cancergencyto.2008.03.015. (source)

Kirsten, Holger; Blume, Mechthild; Emmrich, Frank; Hunzelmann, Nico; Mierau, Rudolf; Rzepka, Rita et al.: No association between systemic sclerosis and C77G polymorphism in the human PTPRC (CD45) gene. J. Rheumatol. 35 (9), S. 1817–1819. (source)

Ender, Joerg; Borger, Michael Andrew; Scholz, Markus; Funkat, Anne-Kathrin; Anwar, Nadeem; Sommer, Marcus et al.: Cardiac surgery fast-track treatment in a postanesthetic care unit: six-month results of the Leipzig fast-track concept. Anesthesiology 109 (1), S. 61–66. DOI: 10.1097/ALN.0b013e31817881b3. (source)

Rehak, Matus; Rehak, Jiri; Müller, Marc; Faude, Susanne; Faude, Frank; Siegemund, Annelie et al.: The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Case-control study and meta-analysis. Thromb. Haemost. 99 (5), S. 925–929. DOI: 10.1160/TH07-11-0658. (source)

Hau, Susann; Reich, Doreen M.; Scholz, Markus; Naumann, Wilfried; Emmrich, Frank; Kamprad, Manja; Boltze, Johannes: Evidence for neuroprotective properties of human umbilical cord blood cells after neuronal hypoxia in vitro. BMC Neurosci 9, S. 30. DOI: 10.1186/1471-2202-9-30. (source)

Scholz, Markus; Niesch, Harald; Steffen, Olaf; Ernst, Baerbel; Loeffler, Markus; Witruk, Evelin; Schwarz, Hans: Impact of chess training on mathematics performance and concentration ability of children with learning disabilities. International Journal of Special Education 23 (3). Online verfügbar unter http://www.internationaljournalofspecialeducation.com/articles.cfm?y=2008&v=23&n=3. (source)

Holland, Heidrun; Koschny, Ronald; Krupp, Wolfgang; Meixensberger, Jürgen; Bauer, Manfred; Schober, Ralf et al.: Cytogenetic and molecular biological characterization of an adult medulloblastoma. Cancer Genet. Cytogenet. 178 (2), S. 104–113. DOI: 10.1016/j.cancergencyto.2007.06.005. (source)

Koschny, Ronald; Holland, Heidrun; Sykora, Jaromir; Haas, Tobias L.; Sprick, Martin R.; Ganten, Tom M. et al.: Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Clin. Cancer Res. 13 (11), S. 3403–3412. DOI: 10.1158/1078-0432.CCR-07-0251. (source)

Kirsten, Holger; Teupser, Daniel; Weissfuss, Jana; Wolfram, Grit; Emmrich, Frank; Ahnert, Peter: Robustness of single-base extension against mismatches at the site of primer attachment in a clinical assay. J. Mol. Med. 85 (4), S. 361–369. DOI: 10.1007/s00109-006-0129-2. (source)

Tönjes, Anke; Scholz, Markus; Fasshauer, Mathias; Kratzsch, Jürgen; Rassoul, Fauci; Stumvoll, Michael; Blüher, Matthias: Beneficial effects of a 4-week exercise program on plasma concentrations of adhesion molecules. Diabetes Care 30 (3), S. e1. DOI: 10.2337/dc06-1760. (source)

Holland, Heidrun; Koschny, Ronald; Krupp, Wolfgang; Meixensberger, Jürgen; Bauer, Manfred; Kirsten, Holger; Ahnert, Peter: Comprehensive cytogenetic characterization of an esthesioneuroblastoma. Cancer Genet. Cytogenet. 173 (2), S. 89–96. DOI: 10.1016/j.cancergencyto.2006.09.024. (source)

Mahr, Sandra; Kirsten, Holger; Mueller, Brigitte: Reply to Loughlin et al. Am J Hum Genet 80 (2), S. 386–387. Online verfügbar unter http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1785335/. (source)

Ahnert, Peter; Kirsten, Holger: Association of ITGAV supports a role of angiogenesis in rheumatoid arthritis. Arthritis Res. Ther. 9 (5), S. 108. DOI: 10.1186/ar2313. (source)

Tönjes, Anke; Scholz, Markus; Loeffler, Markus; Stumvoll, Michael: Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals. Diabetes Care 29 (11), S. 2489–2497. DOI: 10.2337/dc06-0513. (source)

Scholz, Markus; Engel, Christoph; Loeffler, Markus: Model-based design of chemotherapeutic regimens that account for heterogeneity in leucopoenia. Br. J. Haematol. 132 (6), S. 723–735. DOI: 10.1111/j.1365-2141.2005.05957.x. (source)

Kirsten, Holger; Dienst, Steffen; Emmrich, Frank; Ahnert, Peter: CalcDalton: a tool for multiplex genotyping primer design for single-base extension reactions using cleavable primers. BioTechniques 40 (2), S. 158. (source)